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• W2079097293 abstract "To evaluate the extent of the association between hyperhomocysteinaemia and chronic ischaemic heart disease.Unmatched, case-control (1:3) study.Pintores Health Centre, Area 10, Primary Care, Madrid, Spain.Patients of the health centre over 35 with chronic ischaemic heart disease or without it.Consecutive, non-randomized sample. Analysis of cases and controls with chi2 test and odds ratio (OR). The quantitative variables were analysed with the Student's t test.The 76.32% (87/114) of cases had 2 or more cardiovascular risk factors versus 33.56% (99/265) in the control group (P<.0001). Average homocysteinaemia was 10.07 micromol/L (SD, 3.64) in the control group; and 12.74 (SD, 4.59) in the cases group. The difference between the averages (2.67 micromol/L; 95% CI, 1.82-3.52) was significant (P<.001). The difference (16.07%; 95% CI, 6.91-25.23) in hyperhomocysteinaemia (> or =15 micromol/L) between cases (28.95%, 33/114) and controls (12.88%, 38/295) was significant (P=.0001), with an association between hyperhomocysteinaemia and chronic ischaemic heart disease (OR=2.76; 95% CI, 1.62-4.68). This association increased (OR=3.26; 95% CI, 2.07-5.13) when hyperhomocysteinaemia was taken as > or =12 micromol/L, with a significant difference of 27% (95% CI, 16.59-37.41) (P<.0001) between cases (51.75%, 59/114) and controls (24.75%, 73/295).The risk factor of hyperhomocysteinaemia > or =15 micromol/L was significantly associated (OR=2.76) with chronic ischaemic heart disease. This association was greater (OR=3.26) when hyperhomocysteinaemia was taken as > or =12 micromol/L." @default.
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• W2079097293 date "2006-03-01" @default.
• W2079097293 modified "2023-10-17" @default.
• W2079097293 title "Estudio de casos y controles no emparejados: hiperhomocisteinemia y cardiopatía isquémica crónica" @default.
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• W2079097293 doi "https://doi.org/10.1157/13086709" @default.
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