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- W2079100161 abstract "Lentinan (Ajinomoto, Japan) was administrated intraperitoneally (i.p.) and intranasally (i.n.) at different doses (1, 5 and 10 mg/kg) to rats. Effectiveness of Lentinan treatment was evaluated by comparative testing of cell activation (establishing the number, glycolytic and acid phosphatase activity, H2O2 production and killing ability against Salmonella enteritidis and Staphylococcus aureus) at two different compartments–peritoneal and broncho-alveolar cavities. The results indicated that Lentinan induced high-grade activation of peritoneal cells (PCs) and especially of broncho-alveolar cells (BACs) with markedly enhanced effector function (killing ability against S. aureus). Generally, Lentinan, known usually with its parenteral routes of application, can be successful to stimulate the host cell response in the respiratory tract by intranasal route of administration." @default.
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- W2079100161 date "1982-01-01" @default.
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- W2079100161 title "Roles of T cell derived colony stimulating factor(s) induced by a T cell specific adjuvant lentinan in augmentation of T cell repertoire reactivity to lymphokines" @default.
- W2079100161 doi "https://doi.org/10.1016/0192-0561(82)90131-x" @default.
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