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- W2079109817 abstract "The ultrastructure of cuticle formation and the effect of actinomycin-D on cuticle formation were examined in the second molt of Nippostrongylus brasiliensis . At the end of the first molt the rough endoplasmic reticulum of the hypodermis (epidermis) had narrow cisternae. As cuticle formation began the RER cisternae dilated and accumulated a fibrous material. These large fibrous material-containing vesicles then decreased and by the time cuticle deposition was completed they had disappeared. Actinomycin-D prevented the proliferation of RER and the formation of fibrous material-containing vesicles. Actinomycin-D induced several ultrastructural alterations in the hypodermis, the most prominent of which were large crystalline-like inclusions. Other alterations involved the configuration of RER and structure of nucleoli. These morphological aspects of cuticle formation were correlated to the molecular events that control molting." @default.
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- W2079109817 date "1975-10-01" @default.
- W2079109817 modified "2023-09-30" @default.
- W2079109817 title "Cuticle formation in parasitic nematodes: Ultrastructure of molting and the effects of actinomycin-D" @default.
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- W2079109817 doi "https://doi.org/10.1016/s0022-5320(75)80087-6" @default.
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