FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079111307> ?p ?o ?g. }

• W2079111307 endingPage "864" @default.
• W2079111307 startingPage "859" @default.
• W2079111307 abstract "Sensitization to allergens produced by German and American cockroaches is strongly associated with the cause of asthma. Most of the cockroach allergens identified to date have been species specific.The aim of this study was to identify and sequence cross-reactive cockroach allergens.A Periplaneta americana cDNA library was screened with IgE antibody from patients in the United States who were allergic to cockroach and who were sensitized to Blattella germanica.A cDNA clone was isolated that contained an 870-bp sequence with a 695-bp open reading frame, encoding a 231 amino acid protein, molecular weight 26.2 kd. Plaque immunoassays using anti-Bla g 1 and anti-Per a 1 mAbs and a panel of human IgE antibodies showed that the protein expressed by these clones was Per a 1. Sequence homology searches showed that Per a 1 was homologous to 5 previously reported, but unidentified, sequences from B germanica and P americana. These sequences encoded proteins with multiple molecular sizes containing approximately 100 amino acid repeats. The Per a 1 sequence also showed 31% identity to a mosquito precursor protein, ANG12, which may be involved in digestion. The Per a 1 cDNA was expressed in Pichia pastoris to produce purified recombinant allergen (yield, 14 mg/L).The results define the molecular structure and antigenic relationships between a new family of cross-reactive Group 1 allergens produced by both P americana and B germanica. These recombinant allergens and specific mAbs will provide tools to improve the diagnosis and treatment of allergic diseases caused by cockroaches." @default.
• W2079111307 created "2016-06-24" @default.
• W2079111307 creator A5006695127 @default.
• W2079111307 creator A5026913670 @default.
• W2079111307 creator A5049025189 @default.
• W2079111307 creator A5065910573 @default.
• W2079111307 creator A5085395944 @default.
• W2079111307 date "1999-05-01" @default.
• W2079111307 modified "2023-09-26" @default.
• W2079111307 title "Molecular cloning of Per a 1 and definition of the cross-reactive Group 1 cockroach allergens" @default.
• W2079111307 cites W1562326797 @default.
• W2079111307 cites W1579501226 @default.
• W2079111307 cites W1973416875 @default.
• W2079111307 cites W1977706559 @default.
• W2079111307 cites W1984901942 @default.
• W2079111307 cites W2000130110 @default.
• W2079111307 cites W2003544053 @default.
• W2079111307 cites W2007086959 @default.
• W2079111307 cites W2015428834 @default.
• W2079111307 cites W2019737458 @default.
• W2079111307 cites W2039500462 @default.
• W2079111307 cites W2043928652 @default.
• W2079111307 cites W2054325242 @default.
• W2079111307 cites W2061296084 @default.
• W2079111307 cites W2062829477 @default.
• W2079111307 cites W2093711421 @default.
• W2079111307 cites W2111332083 @default.
• W2079111307 cites W2117910695 @default.
• W2079111307 cites W2142456091 @default.
• W2079111307 cites W2144270508 @default.
• W2079111307 cites W2462890753 @default.
• W2079111307 cites W5557961 @default.
• W2079111307 doi "https://doi.org/10.1016/s0091-6749(99)70430-6" @default.
• W2079111307 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10329820" @default.
• W2079111307 hasPublicationYear "1999" @default.
• W2079111307 type Work @default.
• W2079111307 sameAs 2079111307 @default.
• W2079111307 citedByCount "52" @default.
• W2079111307 countsByYear W20791113072012 @default.
• W2079111307 countsByYear W20791113072013 @default.
• W2079111307 countsByYear W20791113072014 @default.
• W2079111307 countsByYear W20791113072015 @default.
• W2079111307 countsByYear W20791113072016 @default.
• W2079111307 countsByYear W20791113072017 @default.
• W2079111307 countsByYear W20791113072018 @default.
• W2079111307 countsByYear W20791113072020 @default.
• W2079111307 countsByYear W20791113072021 @default.
• W2079111307 countsByYear W20791113072022 @default.
• W2079111307 countsByYear W20791113072023 @default.
• W2079111307 crossrefType "journal-article" @default.
• W2079111307 hasAuthorship W2079111307A5006695127 @default.
• W2079111307 hasAuthorship W2079111307A5026913670 @default.
• W2079111307 hasAuthorship W2079111307A5049025189 @default.
• W2079111307 hasAuthorship W2079111307A5065910573 @default.
• W2079111307 hasAuthorship W2079111307A5085395944 @default.
• W2079111307 hasConcept C104317684 @default.
• W2079111307 hasConcept C141105273 @default.
• W2079111307 hasConcept C153911025 @default.
• W2079111307 hasConcept C159654299 @default.
• W2079111307 hasConcept C167625842 @default.
• W2079111307 hasConcept C187882448 @default.
• W2079111307 hasConcept C18903297 @default.
• W2079111307 hasConcept C19924922 @default.
• W2079111307 hasConcept C203014093 @default.
• W2079111307 hasConcept C207480886 @default.
• W2079111307 hasConcept C2776273225 @default.
• W2079111307 hasConcept C2777346155 @default.
• W2079111307 hasConcept C2779808186 @default.
• W2079111307 hasConcept C2780510475 @default.
• W2079111307 hasConcept C2780625307 @default.
• W2079111307 hasConcept C2781372317 @default.
• W2079111307 hasConcept C40767141 @default.
• W2079111307 hasConcept C54355233 @default.
• W2079111307 hasConcept C86803240 @default.
• W2079111307 hasConceptScore W2079111307C104317684 @default.
• W2079111307 hasConceptScore W2079111307C141105273 @default.
• W2079111307 hasConceptScore W2079111307C153911025 @default.
• W2079111307 hasConceptScore W2079111307C159654299 @default.
• W2079111307 hasConceptScore W2079111307C167625842 @default.
• W2079111307 hasConceptScore W2079111307C187882448 @default.
• W2079111307 hasConceptScore W2079111307C18903297 @default.
• W2079111307 hasConceptScore W2079111307C19924922 @default.
• W2079111307 hasConceptScore W2079111307C203014093 @default.
• W2079111307 hasConceptScore W2079111307C207480886 @default.
• W2079111307 hasConceptScore W2079111307C2776273225 @default.
• W2079111307 hasConceptScore W2079111307C2777346155 @default.
• W2079111307 hasConceptScore W2079111307C2779808186 @default.
• W2079111307 hasConceptScore W2079111307C2780510475 @default.
• W2079111307 hasConceptScore W2079111307C2780625307 @default.
• W2079111307 hasConceptScore W2079111307C2781372317 @default.
• W2079111307 hasConceptScore W2079111307C40767141 @default.
• W2079111307 hasConceptScore W2079111307C54355233 @default.
• W2079111307 hasConceptScore W2079111307C86803240 @default.
• W2079111307 hasIssue "5" @default.
• W2079111307 hasLocation W20791113071 @default.
• W2079111307 hasLocation W20791113072 @default.
• W2079111307 hasOpenAccess W2079111307 @default.
• W2079111307 hasPrimaryLocation W20791113071 @default.

• next