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- W2079112981 abstract "ABSTRACT. Purpose: To compare the clinical and bacteriological effects of fucidic acid (Fucithalmic ® : 1.0%) and chloramphenicol (Minims ® : 0.5%) eye drops in neonates with a clinical diagnosis of acute conjunctivitis of suspected bacterial origin. Methods: A total of 456 n ewborns with gestational age > 32 weeks with acute conjunctivitis of suspected bacterial origin acquired within the first 28 days of life were included in the study. They were randomly assigned to a 7‐day treatment with eye drops using either fucidic acid (1.0%) (Fucithalmic ® ) applied twice per day, or chloramphenicol (0.5%) (Minims ® Chloramphenicol) applied six times per day. The subjects were followed up with two visits (on days 1 and 8) and by telephone 2 weeks after the end of treatment. Results: Eighty‐nine per cent of the neonates treated with Fucithalmic ® were cured, compared to 87.9% of those treated with Minims ® Chloramphenicol (n.s). The drug was used as instructed in 90.7% of patients treated with Fucithalmic ® and in 78.0% of those treated with Minims ® Chloramphenicol ( P < 0.001). Conclusion: Treating neonatal conjunctivitis with fucidic acid is easier than with chloramphenicol and is equally effective." @default.
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- W2079112981 date "2002-04-01" @default.
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- W2079112981 title "Treatment of acute neonatal bacterial conjunctivitis: a comparison of fucidic acid to chloramphenicol eye drops" @default.
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- W2079112981 doi "https://doi.org/10.1034/j.1600-0420.2002.800212.x" @default.
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