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• W2079121135 abstract "Abstract Background 2,3-Butanediol is a platform and fuel biochemical that can be efficiently produced from biomass. However, a value-added process for this chemical has not yet been developed. To expand the utilization of 2,3-butanediol produced from biomass, an improved derivative process of 2,3-butanediol is desirable. Results In this study, a Gluconobacter oxydans strain DSM 2003 was found to have the ability to transform 2,3-butanediol into acetoin, a high value feedstock that can be widely used in dairy and cosmetic products, and chemical synthesis. All three stereoisomers, meso -2,3-butanediol, (2 R ,3 R )-2,3-butanediol, and (2 S ,3 S )-2,3-butanediol, could be transformed into acetoin by the strain. After optimization of the bioconversion conditions, the optimum growth temperature for acetoin production by strain DSM 2003 was found to be 30°C and the medium pH was 6.0. With an initial 2,3-butanediol concentration of 40 g/L, acetoin at a high concentration of 89.2 g/L was obtained from 2,3-butanediol by fed-batch bioconversion with a high productivity (1.24 g/L · h) and high yield (0.912 mol/mol). Conclusions G. oxydans DSM 2003 is the first strain that can be used in the direct production of acetoin from 2,3-butanediol. The product concentration and yield of the novel process are both new records for acetoin production. The results demonstrate that the method developed in this study could provide a promising process for efficient acetoin production and industrially produced 2,3-butanediol utilization." @default.
• W2079121135 created "2016-06-24" @default.
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• W2079121135 date "2013-10-31" @default.
• W2079121135 modified "2023-10-18" @default.
• W2079121135 title "Efficient bioconversion of 2,3-butanediol into acetoin using Gluconobacter oxydans DSM 2003" @default.
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• W2079121135 doi "https://doi.org/10.1186/1754-6834-6-155" @default.
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