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- W2079126229 abstract "The mechanisms of photoreception and intracellular signalling in vertebrate photoreceptors have been elucidated in remarkably complete molecular detail. This background has allowed DNA fragments encoding visual pigments and accessory proteins of the cGMP cascade to be cloned. Information about gene structure and amino acid sequences of the protein products suggest that at least two of the proteins in the visual pathway, rhodopsin and G-protein, are members of large families of genes derived from ancient ancestral precursors. Comparison of amino acid sequence information for many members in each family emphasizes the homologies and the important aspects of structure and function of these proteins. The mechanisms used for visual signalling are common to those used by modulatory neurotransmitters, and serve as a prototype for the molecular basis of neuromodulatory signalling." @default.
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- W2079126229 date "1986-01-01" @default.
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- W2079126229 title "Exploring visual transduction with recombinant DNA techniques" @default.
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