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- W2079138151 abstract "The anti-inflammatory and antinociceptive effects of trans-dehydrocrotonin, isolated from the bark of Croton cajucara (Euphorbiaceae), were investigated using several animal models. The trans-dehydrocrotonin produced a significant inhibition of carrageenin-induced paw edema and cotton pellet granuloma in rats. It also inhibited the writhings in mice induced by acetic acid, but did not show a significant effect in the hot-plate test in mice. The LD50 of t-DCTN was 555.0 mg/kg (p.o.) for mice." @default.
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- W2079138151 date "1996-10-01" @default.
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- W2079138151 title "Investigation of Anti-Inflammatory and Antinociceptive Activities of<i>trans</i>-Dehydrocrotonin, a 19-Nor-Clerodane Diterpene from<i>Croton cajucara</i>. Part 1" @default.
- W2079138151 doi "https://doi.org/10.1055/s-2006-957925" @default.
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