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- W2079151231 abstract "Large (>90%) for gestational age (LGA) fetuses are usually identified incidentally. Detection of the LGA fetus should first prompt the provider to rule out incorrect dates and maternal diabetes. Once this is done, consideration should be given to certain overgrowth syndromes, especially if anomalies are present. The overgrowth syndromes have significant clinical and molecular overlap, and are associated with developmental delay, tumors, and other anomalies. Although genetic causes of overgrowth are considered postnatally, they are infrequently diagnosed prenatally. Here, we review prenatal sonographic findings in fetal overgrowth syndromes, including Pallister-Killian, Beckwith-Wiedemann, Sotos, Perlman, and Simpson-Golabi-Behmel. We also discuss prenatal diagnosis options and recurrence risks. Copyright © 2009 John Wiley & Sons, Ltd." @default.
- W2079151231 created "2016-06-24" @default.
- W2079151231 creator A5041013343 @default.
- W2079151231 creator A5081715355 @default.
- W2079151231 date "2009-07-16" @default.
- W2079151231 modified "2023-10-12" @default.
- W2079151231 title "Genetic considerations in the prenatal diagnosis of overgrowth syndromes" @default.
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- W2079151231 doi "https://doi.org/10.1002/pd.2319" @default.
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