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• W2079156680 abstract "Occlusion and reopening of the lumen of the spinal cord, two processes believed to be involved in early brain enlargement, were examined in chick embryos to determine what morphological features characterize these events. Occlusion begins at a particular craniocaudal level near the time that the neural folds become apposed in the dorsal midline and blocklike somites form from the segmental plates. During occlusion, the apical sides of the lateral walls of the neural tube are in close apposition. Interdigitating apical surface protrusions, cross-luminal intercellular junctions, and abundant cell-surface materials are lacking. Reopening has occurred by about stage 20 throughout most of the craniocaudal extent of the spinal cord. A lumen suddenly appears during this process, but correlated structural changes that might account for such a dramatic change in morphology were undetectable. Reopening involves the release of the forces that previously maintained occlusion, or the generation of new forces that overcome those causing occlusion, but what these forces are remains to be determined. Observations suggest that forces generated outside of the neural tube might be largely responsible for occlusion, and experiments are in progress to test this possibility." @default.
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• W2079156680 date "1984-06-01" @default.
• W2079156680 modified "2023-09-25" @default.
• W2079156680 title "Descriptive studies of occlusion and reopening of the spinal canal of the early chick embryo" @default.
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• W2079156680 doi "https://doi.org/10.1002/ar.1092090211" @default.
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