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- W2079159166 abstract "To investigate the hypothesis that the human endogenous sequence ERV-3 has a function, we have cloned and expressed the transmembrane region of its envelope gene and raised specific antibodies to the fusion protein and to a synthetic peptide. These antibodies reacted with a 65-kDa polypeptide which constituted approximately 0.1% of the cellular protein in syncytiotrophoblasts in placenta. The evolutionary conservation and abundant expression of this endogenous retroviral protein in a specific cell type support the concept of a biological function. The similarity of a domain of ERV-3 env to putative immunosuppressive p15E sequences suggests that ERV-3 might form part of the placental immunosuppressive barrier between mother and foetus." @default.
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- W2079159166 date "1995-08-01" @default.
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- W2079159166 title "Abundance of an Endogenous Retroviral Envelope Protein in Placental Trophoblasts Suggests a Biological Function" @default.
- W2079159166 doi "https://doi.org/10.1006/viro.1995.1442" @default.
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