FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079165221> ?p ?o ?g. }

• W2079165221 endingPage "43" @default.
• W2079165221 startingPage "31" @default.
• W2079165221 abstract "We examined whether Gbx2 is required after embryonic day 9 (E9) to repress Otx2 in the cerebellar anlage and position the midbrain/hindbrain organizer. In contrast to Gbx2 null mutants, mice lacking Gbx2 in rhombomere 1 (r1) after E9 (Gbx2-CKO) are viable and develop a cerebellum. A Gbx2-independent pathway can repress Otx2 in r1 after E9. Mid/hindbrain organizer gene expression, however, continues to be dependent on Gbx2. We found that Fgf8 expression normally correlates with the isthmus where cells undergo low proliferation and that in Gbx2-CKO mutants this domain is expanded. We propose that Fgf8 permits lateral cerebellar development through repression of Otx2 and also suppresses medial cerebellar growth in Gbx2-CKO embryos. Our work has uncovered distinct requirements for Gbx2 during cerebellum formation and provided a model for how a transcription factor can play multiple roles during development." @default.
• W2079165221 created "2016-06-24" @default.
• W2079165221 creator A5023939064 @default.
• W2079165221 creator A5041948504 @default.
• W2079165221 creator A5057592027 @default.
• W2079165221 date "2002-09-01" @default.
• W2079165221 modified "2023-10-14" @default.
• W2079165221 title "Changing Requirements for Gbx2 in Development of the Cerebellum and Maintenance of the Mid/Hindbrain Organizer" @default.
• W2079165221 cites W1499845615 @default.
• W2079165221 cites W1598052913 @default.
• W2079165221 cites W1618939505 @default.
• W2079165221 cites W1658437261 @default.
• W2079165221 cites W1768274470 @default.
• W2079165221 cites W1853890854 @default.
• W2079165221 cites W1922106993 @default.
• W2079165221 cites W1953764490 @default.
• W2079165221 cites W1965580640 @default.
• W2079165221 cites W1997190412 @default.
• W2079165221 cites W2006136865 @default.
• W2079165221 cites W2006783364 @default.
• W2079165221 cites W2006892479 @default.
• W2079165221 cites W2010055658 @default.
• W2079165221 cites W2026613468 @default.
• W2079165221 cites W2052478761 @default.
• W2079165221 cites W2059241101 @default.
• W2079165221 cites W2061614290 @default.
• W2079165221 cites W2087025369 @default.
• W2079165221 cites W2091626902 @default.
• W2079165221 cites W2107736130 @default.
• W2079165221 cites W2110496051 @default.
• W2079165221 cites W2111334408 @default.
• W2079165221 cites W2119800709 @default.
• W2079165221 cites W2127510589 @default.
• W2079165221 cites W2129211286 @default.
• W2079165221 cites W2139727029 @default.
• W2079165221 cites W2142940829 @default.
• W2079165221 cites W2150013759 @default.
• W2079165221 cites W2151794618 @default.
• W2079165221 cites W2157735031 @default.
• W2079165221 cites W2165695219 @default.
• W2079165221 cites W2183066763 @default.
• W2079165221 cites W2183334517 @default.
• W2079165221 cites W2187117368 @default.
• W2079165221 cites W2187208469 @default.
• W2079165221 cites W2332470956 @default.
• W2079165221 cites W2444619274 @default.
• W2079165221 doi "https://doi.org/10.1016/s0896-6273(02)00935-2" @default.
• W2079165221 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12367504" @default.
• W2079165221 hasPublicationYear "2002" @default.
• W2079165221 type Work @default.
• W2079165221 sameAs 2079165221 @default.
• W2079165221 citedByCount "116" @default.
• W2079165221 countsByYear W20791652212012 @default.
• W2079165221 countsByYear W20791652212013 @default.
• W2079165221 countsByYear W20791652212014 @default.
• W2079165221 countsByYear W20791652212015 @default.
• W2079165221 countsByYear W20791652212016 @default.
• W2079165221 countsByYear W20791652212017 @default.
• W2079165221 countsByYear W20791652212018 @default.
• W2079165221 countsByYear W20791652212019 @default.
• W2079165221 countsByYear W20791652212020 @default.
• W2079165221 countsByYear W20791652212021 @default.
• W2079165221 countsByYear W20791652212022 @default.
• W2079165221 countsByYear W20791652212023 @default.
• W2079165221 crossrefType "journal-article" @default.
• W2079165221 hasAuthorship W2079165221A5023939064 @default.
• W2079165221 hasAuthorship W2079165221A5041948504 @default.
• W2079165221 hasAuthorship W2079165221A5057592027 @default.
• W2079165221 hasBestOaLocation W20791652211 @default.
• W2079165221 hasConcept C104317684 @default.
• W2079165221 hasConcept C121587040 @default.
• W2079165221 hasConcept C145103041 @default.
• W2079165221 hasConcept C169760540 @default.
• W2079165221 hasConcept C170493617 @default.
• W2079165221 hasConcept C2776094402 @default.
• W2079165221 hasConcept C2777075493 @default.
• W2079165221 hasConcept C2779652256 @default.
• W2079165221 hasConcept C529278444 @default.
• W2079165221 hasConcept C54355233 @default.
• W2079165221 hasConcept C552161191 @default.
• W2079165221 hasConcept C63101894 @default.
• W2079165221 hasConcept C74373430 @default.
• W2079165221 hasConcept C86339819 @default.
• W2079165221 hasConcept C86803240 @default.
• W2079165221 hasConceptScore W2079165221C104317684 @default.
• W2079165221 hasConceptScore W2079165221C121587040 @default.
• W2079165221 hasConceptScore W2079165221C145103041 @default.
• W2079165221 hasConceptScore W2079165221C169760540 @default.
• W2079165221 hasConceptScore W2079165221C170493617 @default.
• W2079165221 hasConceptScore W2079165221C2776094402 @default.
• W2079165221 hasConceptScore W2079165221C2777075493 @default.
• W2079165221 hasConceptScore W2079165221C2779652256 @default.
• W2079165221 hasConceptScore W2079165221C529278444 @default.
• W2079165221 hasConceptScore W2079165221C54355233 @default.
• W2079165221 hasConceptScore W2079165221C552161191 @default.
• W2079165221 hasConceptScore W2079165221C63101894 @default.
• W2079165221 hasConceptScore W2079165221C74373430 @default.
• W2079165221 hasConceptScore W2079165221C86339819 @default.

• next