Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079170273> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2079170273 endingPage "175" @default.
- W2079170273 startingPage "163" @default.
- W2079170273 abstract "Dihydroflavins are facile reducing agents and potent nucleophiles. The dihydroflavin nucleophilic reactivity, as measured by the rate of covalent flavin adduct formation with tetrahydronaphthalene epoxides, is comparable to that of the thiolate anion (Y. T. Lee and J. F. Fisher (1993) J. Org. Chem.58, 3712). In these reactions there appears subsequent to the nucleophilic cleavage of the epoxide by the dihydroflavin the product corresponding to formal hydride reduction product (at the benzylic carbon) of these epoxides. Thus the reaction of (±)-1a,2,3, 7b-tetrahydro-(1aα,2α,3β,7bα)-naphth[1,2-b]oxirene-2,3-diol (1), (±)-1a,2,3,7b-tetrahydro-(1aα,2β,3α,7bα)-naphth[1,2-b]oxirene-2,3-diol (2), and (±)-1a,2,3,7b-tetrahydro-(1aα,7bα)-naphth[1,2-b]oxirene (3) in 9:1 (v/v) aqueous Tris buffer–dioxane, at both acidic and neutral pH, with FMNH2 and 1,5-dihydrolumiflavin (LFH2) gave (following covalent flavin–epoxide adduct formation) the products having a methylene group at the benzylic position. The reduction product yield was proportional to the yield of the N(5) flavin–epoxide adduct intermediate, and the rate of the reaction was proportional to the dihydroflavin concentration. These observations are consistent with these reduction products resulting from bimolecular reaction between the dihydroflavin–epoxide adduct and a second molecule of dihydroflavin." @default.
- W2079170273 created "2016-06-24" @default.
- W2079170273 creator A5048366041 @default.
- W2079170273 creator A5074738498 @default.
- W2079170273 date "2000-06-01" @default.
- W2079170273 modified "2023-10-16" @default.
- W2079170273 title "A Mechanistic Study of the Dihydroflavin Reductive Cleavage of the Dihydroflavin–Tetrahydronaphthalene Epoxide Adducts" @default.
- W2079170273 cites W1036662423 @default.
- W2079170273 cites W1984380458 @default.
- W2079170273 cites W1994379492 @default.
- W2079170273 cites W1998335176 @default.
- W2079170273 cites W2033552740 @default.
- W2079170273 cites W2051826669 @default.
- W2079170273 cites W2069551450 @default.
- W2079170273 cites W2078363670 @default.
- W2079170273 cites W2083559130 @default.
- W2079170273 cites W2129412622 @default.
- W2079170273 cites W2314219399 @default.
- W2079170273 cites W2415921883 @default.
- W2079170273 cites W2951954942 @default.
- W2079170273 cites W957475716 @default.
- W2079170273 doi "https://doi.org/10.1006/bioo.2000.1171" @default.
- W2079170273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10915554" @default.
- W2079170273 hasPublicationYear "2000" @default.
- W2079170273 type Work @default.
- W2079170273 sameAs 2079170273 @default.
- W2079170273 citedByCount "3" @default.
- W2079170273 countsByYear W20791702732012 @default.
- W2079170273 crossrefType "journal-article" @default.
- W2079170273 hasAuthorship W2079170273A5048366041 @default.
- W2079170273 hasAuthorship W2079170273A5074738498 @default.
- W2079170273 hasConcept C108204754 @default.
- W2079170273 hasConcept C155647269 @default.
- W2079170273 hasConcept C161790260 @default.
- W2079170273 hasConcept C178790620 @default.
- W2079170273 hasConcept C178907741 @default.
- W2079170273 hasConcept C181199279 @default.
- W2079170273 hasConcept C185592680 @default.
- W2079170273 hasConcept C2776920199 @default.
- W2079170273 hasConcept C2777454769 @default.
- W2079170273 hasConcept C2779515768 @default.
- W2079170273 hasConcept C33093398 @default.
- W2079170273 hasConcept C71240020 @default.
- W2079170273 hasConceptScore W2079170273C108204754 @default.
- W2079170273 hasConceptScore W2079170273C155647269 @default.
- W2079170273 hasConceptScore W2079170273C161790260 @default.
- W2079170273 hasConceptScore W2079170273C178790620 @default.
- W2079170273 hasConceptScore W2079170273C178907741 @default.
- W2079170273 hasConceptScore W2079170273C181199279 @default.
- W2079170273 hasConceptScore W2079170273C185592680 @default.
- W2079170273 hasConceptScore W2079170273C2776920199 @default.
- W2079170273 hasConceptScore W2079170273C2777454769 @default.
- W2079170273 hasConceptScore W2079170273C2779515768 @default.
- W2079170273 hasConceptScore W2079170273C33093398 @default.
- W2079170273 hasConceptScore W2079170273C71240020 @default.
- W2079170273 hasIssue "3" @default.
- W2079170273 hasLocation W20791702731 @default.
- W2079170273 hasLocation W20791702732 @default.
- W2079170273 hasOpenAccess W2079170273 @default.
- W2079170273 hasPrimaryLocation W20791702731 @default.
- W2079170273 hasRelatedWork W140098009 @default.
- W2079170273 hasRelatedWork W1968542886 @default.
- W2079170273 hasRelatedWork W1997628034 @default.
- W2079170273 hasRelatedWork W2033177915 @default.
- W2079170273 hasRelatedWork W2078976938 @default.
- W2079170273 hasRelatedWork W2088538647 @default.
- W2079170273 hasRelatedWork W2143493576 @default.
- W2079170273 hasRelatedWork W2443583858 @default.
- W2079170273 hasRelatedWork W2758839128 @default.
- W2079170273 hasRelatedWork W2739652435 @default.
- W2079170273 hasVolume "28" @default.
- W2079170273 isParatext "false" @default.
- W2079170273 isRetracted "false" @default.
- W2079170273 magId "2079170273" @default.
- W2079170273 workType "article" @default.