FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079175028> ?p ?o ?g. }

• W2079175028 endingPage "50" @default.
• W2079175028 startingPage "41" @default.
• W2079175028 abstract "Paraffin-embedded sections of 99 human adrenal and extra-adrenal paragangliomas were analyzed by the indirect immunoperoxidase technique for the presence of neuron-specific enolase (NSE) and 10 neuropeptides. Each showed diffuse staining for NSE. Most tumors were positive for [Leu5]-enkephalin (76 per cent), [Met5]-enkephalin (75 per cent), somatostatin (67 per cent), and pancreatic polypeptide (51 per cent), followed by vasoactive intestinal polypeptide (VIP) (43 per cent), substance P (31 per cent), ACTH (28 per cent), calcitonin (23 per cent), bombesin (15 per cent), and neurotensin (12 per cent). The neuropeptides paralleled to a large extent those normally found in the sympathetic nervous system. Clinically malignant paragangliomas (n=25) with proven regional or distant metastases expressed considerably fewer neuropeptides, although the spectrum of those seen remained similar. Malignant paragangliomas contained an average of two neuropeptides per tumor, in contrast to five for the benign tumors (P<0.05). Logistic regression analysis of staining results revealed that the paucity of enkephalins, somatostatin, pancreatic polypeptide, and VIP along with the patient's sex was predictive of clinical malignancy. Our results show a definite relationship between expression of neuropeptides and the biologic behavior of these paragangliomas." @default.
• W2079175028 created "2016-06-24" @default.
• W2079175028 creator A5010524983 @default.
• W2079175028 creator A5044239219 @default.
• W2079175028 creator A5048845488 @default.
• W2079175028 creator A5074936625 @default.
• W2079175028 date "1988-01-01" @default.
• W2079175028 modified "2023-10-03" @default.
• W2079175028 title "Decreased expression of neuropeptides in malignant paragangliomas: An immunohistochemical study" @default.
• W2079175028 cites W1563546627 @default.
• W2079175028 cites W1647422859 @default.
• W2079175028 cites W1965237421 @default.
• W2079175028 cites W1971229911 @default.
• W2079175028 cites W1974950498 @default.
• W2079175028 cites W1978856958 @default.
• W2079175028 cites W1989224764 @default.
• W2079175028 cites W1990171370 @default.
• W2079175028 cites W1995892877 @default.
• W2079175028 cites W2000319479 @default.
• W2079175028 cites W2007471327 @default.
• W2079175028 cites W2007903907 @default.
• W2079175028 cites W2010051841 @default.
• W2079175028 cites W2010957493 @default.
• W2079175028 cites W2018688254 @default.
• W2079175028 cites W2020232192 @default.
• W2079175028 cites W2024041920 @default.
• W2079175028 cites W2033665745 @default.
• W2079175028 cites W2034546387 @default.
• W2079175028 cites W2043619363 @default.
• W2079175028 cites W2056399175 @default.
• W2079175028 cites W2057635778 @default.
• W2079175028 cites W2063868174 @default.
• W2079175028 cites W2070939273 @default.
• W2079175028 cites W2072735318 @default.
• W2079175028 cites W2073745326 @default.
• W2079175028 cites W2084185303 @default.
• W2079175028 cites W2084530950 @default.
• W2079175028 cites W2089360902 @default.
• W2079175028 cites W2089904381 @default.
• W2079175028 cites W2128732298 @default.
• W2079175028 cites W2146236327 @default.
• W2079175028 cites W2162524861 @default.
• W2079175028 cites W2165740658 @default.
• W2079175028 cites W2178951657 @default.
• W2079175028 cites W2327061927 @default.
• W2079175028 cites W2339157379 @default.
• W2079175028 cites W4254531960 @default.
• W2079175028 doi "https://doi.org/10.1016/s0046-8177(88)80314-9" @default.
• W2079175028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2447010" @default.
• W2079175028 hasPublicationYear "1988" @default.
• W2079175028 type Work @default.
• W2079175028 sameAs 2079175028 @default.
• W2079175028 citedByCount "74" @default.
• W2079175028 countsByYear W20791750282015 @default.
• W2079175028 countsByYear W20791750282016 @default.
• W2079175028 countsByYear W20791750282017 @default.
• W2079175028 countsByYear W20791750282018 @default.
• W2079175028 countsByYear W20791750282019 @default.
• W2079175028 countsByYear W20791750282020 @default.
• W2079175028 countsByYear W20791750282021 @default.
• W2079175028 crossrefType "journal-article" @default.
• W2079175028 hasAuthorship W2079175028A5010524983 @default.
• W2079175028 hasAuthorship W2079175028A5044239219 @default.
• W2079175028 hasAuthorship W2079175028A5048845488 @default.
• W2079175028 hasAuthorship W2079175028A5074936625 @default.
• W2079175028 hasConcept C118303440 @default.
• W2079175028 hasConcept C126322002 @default.
• W2079175028 hasConcept C128102431 @default.
• W2079175028 hasConcept C134018914 @default.
• W2079175028 hasConcept C142724271 @default.
• W2079175028 hasConcept C159654299 @default.
• W2079175028 hasConcept C170493617 @default.
• W2079175028 hasConcept C188618488 @default.
• W2079175028 hasConcept C203014093 @default.
• W2079175028 hasConcept C204232928 @default.
• W2079175028 hasConcept C2776297358 @default.
• W2079175028 hasConcept C2776533618 @default.
• W2079175028 hasConcept C2776734335 @default.
• W2079175028 hasConcept C2778108375 @default.
• W2079175028 hasConcept C2778563252 @default.
• W2079175028 hasConcept C2779399171 @default.
• W2079175028 hasConcept C2779627488 @default.
• W2079175028 hasConcept C542903549 @default.
• W2079175028 hasConcept C71315377 @default.
• W2079175028 hasConcept C71924100 @default.
• W2079175028 hasConcept C8330315 @default.
• W2079175028 hasConcept C93984277 @default.
• W2079175028 hasConceptScore W2079175028C118303440 @default.
• W2079175028 hasConceptScore W2079175028C126322002 @default.
• W2079175028 hasConceptScore W2079175028C128102431 @default.
• W2079175028 hasConceptScore W2079175028C134018914 @default.
• W2079175028 hasConceptScore W2079175028C142724271 @default.
• W2079175028 hasConceptScore W2079175028C159654299 @default.
• W2079175028 hasConceptScore W2079175028C170493617 @default.
• W2079175028 hasConceptScore W2079175028C188618488 @default.
• W2079175028 hasConceptScore W2079175028C203014093 @default.
• W2079175028 hasConceptScore W2079175028C204232928 @default.
• W2079175028 hasConceptScore W2079175028C2776297358 @default.

• next