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- W2079180810 abstract "A new technique for treating skinned cardiac muscle fibers has been developed in which troponin I is extracted, giving rise to unregulated fibers. The effect of the 12‐residue troponin I peptide on these fibers indicates that this region of troponin I is solely responsible for muscle relaxation (inhibition of force). Furthermore, troponin I peptide‐troponin C reconstituted fibers are stable through several contraction‐relaxation cycles indicating the peptide can switch binding sites between actin and troponin C. The troponin I peptide can substitute for the native protein as part of the calcium‐sensitive molecular switch that controls muscle regulation." @default.
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- W2079180810 date "1993-06-01" @default.
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- W2079180810 title "A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction" @default.
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- W2079180810 doi "https://doi.org/10.1016/0014-5793(93)81344-y" @default.
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