FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079181008> ?p ?o ?g. }

• W2079181008 endingPage "1294" @default.
• W2079181008 startingPage "1290" @default.
• W2079181008 abstract "To study genetic loci influencing obesity in nuclear families with type 2 diabetes, we performed a genome-wide screen with 325 microsatellite markers that had an average spacing of 11 cM and a mean heterozygosity of ∼75% covering all 22 autosomes. Genotype data were obtained from 562 individuals from 178 families from the Breda Study Cohort. These families were determined to have at least two members with type 2 diabetes. As a measure of obesity, the BMI of each diabetes patient was determined. The genotypes were analyzed using variance components (VCs) analysis implemented in GENEHUNTER 2 to determine quantitative trait loci influencing BMI. The VC analysis revealed two genomic regions showing VC logarithm of odds (LOD) scores ≥1.0 on chromosome 1 and chromosome 11. The regions of interest on both chromosomes were further investigated by fine-mapping with additional markers, resulting in a VC LOD score of 1.5 on chromosome 1q and a VC LOD of 2.4 on chromosome 11q. The locus on chromosome 1 has been implicated previously in diabetes. The locus on chromosome 11 has been implicated previously in diabetes and obesity. Our study to determine linkage for BMI confirms the presence of quantitative trait loci influencing obesity in subjects with type 2 diabetes on chromosomes 1q31-q42 and 11q14-q24." @default.
• W2079181008 created "2016-06-24" @default.
• W2079181008 creator A5001761419 @default.
• W2079181008 creator A5032911059 @default.
• W2079181008 creator A5035504682 @default.
• W2079181008 creator A5040142094 @default.
• W2079181008 creator A5060460490 @default.
• W2079181008 creator A5064509518 @default.
• W2079181008 date "2003-11-01" @default.
• W2079181008 modified "2023-09-27" @default.
• W2079181008 title "Variance-Component Analysis of Obesity in Type 2 Diabetes Confirms Loci on Chromosomes 1q and 11q" @default.
• W2079181008 cites W1971185974 @default.
• W2079181008 cites W1976741643 @default.
• W2079181008 cites W1984513597 @default.
• W2079181008 cites W1985570398 @default.
• W2079181008 cites W2018135697 @default.
• W2079181008 cites W2040845149 @default.
• W2079181008 cites W2048667936 @default.
• W2079181008 cites W2059713787 @default.
• W2079181008 cites W2069558876 @default.
• W2079181008 cites W2085236608 @default.
• W2079181008 cites W2100403796 @default.
• W2079181008 cites W2104310970 @default.
• W2079181008 cites W2106607849 @default.
• W2079181008 cites W2107070633 @default.
• W2079181008 cites W2135082450 @default.
• W2079181008 cites W2135784233 @default.
• W2079181008 cites W2144402304 @default.
• W2079181008 cites W2145433713 @default.
• W2079181008 cites W2161381121 @default.
• W2079181008 cites W2915852991 @default.
• W2079181008 doi "https://doi.org/10.1038/oby.2003.175" @default.
• W2079181008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14627748" @default.
• W2079181008 hasPublicationYear "2003" @default.
• W2079181008 type Work @default.
• W2079181008 sameAs 2079181008 @default.
• W2079181008 citedByCount "16" @default.
• W2079181008 countsByYear W20791810082012 @default.
• W2079181008 countsByYear W20791810082013 @default.
• W2079181008 countsByYear W20791810082016 @default.
• W2079181008 countsByYear W20791810082019 @default.
• W2079181008 crossrefType "journal-article" @default.
• W2079181008 hasAuthorship W2079181008A5001761419 @default.
• W2079181008 hasAuthorship W2079181008A5032911059 @default.
• W2079181008 hasAuthorship W2079181008A5035504682 @default.
• W2079181008 hasAuthorship W2079181008A5040142094 @default.
• W2079181008 hasAuthorship W2079181008A5060460490 @default.
• W2079181008 hasAuthorship W2079181008A5064509518 @default.
• W2079181008 hasBestOaLocation W20791810081 @default.
• W2079181008 hasConcept C104317684 @default.
• W2079181008 hasConcept C134018914 @default.
• W2079181008 hasConcept C134925867 @default.
• W2079181008 hasConcept C135763542 @default.
• W2079181008 hasConcept C142870003 @default.
• W2079181008 hasConcept C180754005 @default.
• W2079181008 hasConcept C2777180221 @default.
• W2079181008 hasConcept C30481170 @default.
• W2079181008 hasConcept C511355011 @default.
• W2079181008 hasConcept C54355233 @default.
• W2079181008 hasConcept C555293320 @default.
• W2079181008 hasConcept C61320498 @default.
• W2079181008 hasConcept C81941488 @default.
• W2079181008 hasConcept C84597430 @default.
• W2079181008 hasConcept C86803240 @default.
• W2079181008 hasConceptScore W2079181008C104317684 @default.
• W2079181008 hasConceptScore W2079181008C134018914 @default.
• W2079181008 hasConceptScore W2079181008C134925867 @default.
• W2079181008 hasConceptScore W2079181008C135763542 @default.
• W2079181008 hasConceptScore W2079181008C142870003 @default.
• W2079181008 hasConceptScore W2079181008C180754005 @default.
• W2079181008 hasConceptScore W2079181008C2777180221 @default.
• W2079181008 hasConceptScore W2079181008C30481170 @default.
• W2079181008 hasConceptScore W2079181008C511355011 @default.
• W2079181008 hasConceptScore W2079181008C54355233 @default.
• W2079181008 hasConceptScore W2079181008C555293320 @default.
• W2079181008 hasConceptScore W2079181008C61320498 @default.
• W2079181008 hasConceptScore W2079181008C81941488 @default.
• W2079181008 hasConceptScore W2079181008C84597430 @default.
• W2079181008 hasConceptScore W2079181008C86803240 @default.
• W2079181008 hasIssue "11" @default.
• W2079181008 hasLocation W20791810081 @default.
• W2079181008 hasLocation W20791810082 @default.
• W2079181008 hasLocation W20791810083 @default.
• W2079181008 hasOpenAccess W2079181008 @default.
• W2079181008 hasPrimaryLocation W20791810081 @default.
• W2079181008 hasRelatedWork W1846743152 @default.
• W2079181008 hasRelatedWork W1969524910 @default.
• W2079181008 hasRelatedWork W2032139146 @default.
• W2079181008 hasRelatedWork W2039482405 @default.
• W2079181008 hasRelatedWork W2042150211 @default.
• W2079181008 hasRelatedWork W2046156759 @default.
• W2079181008 hasRelatedWork W2066651106 @default.
• W2079181008 hasRelatedWork W2132888958 @default.
• W2079181008 hasRelatedWork W2145533817 @default.
• W2079181008 hasRelatedWork W2158946780 @default.
• W2079181008 hasVolume "11" @default.
• W2079181008 isParatext "false" @default.
• W2079181008 isRetracted "false" @default.

• next