FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079182665> ?p ?o ?g. }

• W2079182665 endingPage "1009" @default.
• W2079182665 startingPage "1003" @default.
• W2079182665 abstract "Two-dimensional linear ion trap mass spectrometers are rapidly becoming the new workhorse instruments for shotgun proteomic analysis of complex peptide mixtures. The objective of this study was to compare the potential for false positive peptide sequence matches between a two-dimensional ion trap instrument and a traditional, three-dimensional ion trap instrument. Through the comparative analysis of a complex protein sample, we found that in order to minimize false positive sequence matches, sequence match scoring criteria must be more stringent for data from the two-dimensional ion trap compared to the three-dimensional ion trap data. Given this increased potential for false positives, we also investigated two potential filtering strategies to reduce the false positive matches for data derived from the two-dimensional ion trap, including trypsin enzyme cleavage filtering, and the addition of peptide physicochemical information as a constraint, specifically peptide isoelectric point. The results described here provide a cautionary tale to researchers, demonstrating the need for careful analysis of MS/MS data from this new class of ion trap instruments, as well as the effectiveness of trypsin enzyme cleavage filtering and peptide pI information in maximizing high confidence protein identifications from this powerful proteomic instrumentation." @default.
• W2079182665 created "2016-06-24" @default.
• W2079182665 creator A5017175864 @default.
• W2079182665 creator A5032618881 @default.
• W2079182665 date "2006-03-11" @default.
• W2079182665 modified "2023-10-18" @default.
• W2079182665 title "Trade-Off between High Sensitivity and Increased Potential for False Positive Peptide Sequence Matches Using a Two-Dimensional Linear Ion Trap for Tandem Mass Spectrometry-Based Proteomics" @default.
• W2079182665 cites W1597678601 @default.
• W2079182665 cites W1963894076 @default.
• W2079182665 cites W1970696723 @default.
• W2079182665 cites W1973516598 @default.
• W2079182665 cites W1979319235 @default.
• W2079182665 cites W1981593008 @default.
• W2079182665 cites W1988515943 @default.
• W2079182665 cites W1996600592 @default.
• W2079182665 cites W1999676604 @default.
• W2079182665 cites W2006290622 @default.
• W2079182665 cites W2007426793 @default.
• W2079182665 cites W2025339182 @default.
• W2079182665 cites W2033492963 @default.
• W2079182665 cites W2044690556 @default.
• W2079182665 cites W2050079763 @default.
• W2079182665 cites W2085317185 @default.
• W2079182665 cites W2110603815 @default.
• W2079182665 cites W2112078820 @default.
• W2079182665 cites W2116029572 @default.
• W2079182665 cites W2116200464 @default.
• W2079182665 cites W2118103468 @default.
• W2079182665 cites W2137072570 @default.
• W2079182665 cites W2150746288 @default.
• W2079182665 cites W2153132589 @default.
• W2079182665 cites W2153181113 @default.
• W2079182665 cites W2161254494 @default.
• W2079182665 doi "https://doi.org/10.1021/pr050472i" @default.
• W2079182665 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16602709" @default.
• W2079182665 hasPublicationYear "2006" @default.
• W2079182665 type Work @default.
• W2079182665 sameAs 2079182665 @default.
• W2079182665 citedByCount "43" @default.
• W2079182665 countsByYear W20791826652015 @default.
• W2079182665 countsByYear W20791826652017 @default.
• W2079182665 countsByYear W20791826652018 @default.
• W2079182665 countsByYear W20791826652021 @default.
• W2079182665 crossrefType "journal-article" @default.
• W2079182665 hasAuthorship W2079182665A5017175864 @default.
• W2079182665 hasAuthorship W2079182665A5032618881 @default.
• W2079182665 hasConcept C104317684 @default.
• W2079182665 hasConcept C106289968 @default.
• W2079182665 hasConcept C112979427 @default.
• W2079182665 hasConcept C113196181 @default.
• W2079182665 hasConcept C121099081 @default.
• W2079182665 hasConcept C121332964 @default.
• W2079182665 hasConcept C13762613 @default.
• W2079182665 hasConcept C153294291 @default.
• W2079182665 hasConcept C154945302 @default.
• W2079182665 hasConcept C162356407 @default.
• W2079182665 hasConcept C185592680 @default.
• W2079182665 hasConcept C202157981 @default.
• W2079182665 hasConcept C27420735 @default.
• W2079182665 hasConcept C2779281246 @default.
• W2079182665 hasConcept C27826464 @default.
• W2079182665 hasConcept C31827203 @default.
• W2079182665 hasConcept C41008148 @default.
• W2079182665 hasConcept C43617362 @default.
• W2079182665 hasConcept C46111723 @default.
• W2079182665 hasConcept C55493867 @default.
• W2079182665 hasConcept C64869954 @default.
• W2079182665 hasConcept C68289359 @default.
• W2079182665 hasConceptScore W2079182665C104317684 @default.
• W2079182665 hasConceptScore W2079182665C106289968 @default.
• W2079182665 hasConceptScore W2079182665C112979427 @default.
• W2079182665 hasConceptScore W2079182665C113196181 @default.
• W2079182665 hasConceptScore W2079182665C121099081 @default.
• W2079182665 hasConceptScore W2079182665C121332964 @default.
• W2079182665 hasConceptScore W2079182665C13762613 @default.
• W2079182665 hasConceptScore W2079182665C153294291 @default.
• W2079182665 hasConceptScore W2079182665C154945302 @default.
• W2079182665 hasConceptScore W2079182665C162356407 @default.
• W2079182665 hasConceptScore W2079182665C185592680 @default.
• W2079182665 hasConceptScore W2079182665C202157981 @default.
• W2079182665 hasConceptScore W2079182665C27420735 @default.
• W2079182665 hasConceptScore W2079182665C2779281246 @default.
• W2079182665 hasConceptScore W2079182665C27826464 @default.
• W2079182665 hasConceptScore W2079182665C31827203 @default.
• W2079182665 hasConceptScore W2079182665C41008148 @default.
• W2079182665 hasConceptScore W2079182665C43617362 @default.
• W2079182665 hasConceptScore W2079182665C46111723 @default.
• W2079182665 hasConceptScore W2079182665C55493867 @default.
• W2079182665 hasConceptScore W2079182665C64869954 @default.
• W2079182665 hasConceptScore W2079182665C68289359 @default.
• W2079182665 hasIssue "4" @default.
• W2079182665 hasLocation W20791826651 @default.
• W2079182665 hasLocation W20791826652 @default.
• W2079182665 hasOpenAccess W2079182665 @default.
• W2079182665 hasPrimaryLocation W20791826651 @default.
• W2079182665 hasRelatedWork W2008863376 @default.
• W2079182665 hasRelatedWork W2009268510 @default.
• W2079182665 hasRelatedWork W2023959652 @default.

• next