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• W2079183564 abstract "No AccessJournal of UrologyClinical Urology: Original Article1 Jul 1997Renal Cell Carcinoma of Native Kidneys: Prospective Study of 129 Renal Transplant Patients Jean-Dominique Doublet, Marie-Noelle Peraldi, Bernard Gattegno, Philippe Thibault, and Jean-Daniel Sraer Jean-Dominique DoubletJean-Dominique Doublet More articles by this author , Marie-Noelle PeraldiMarie-Noelle Peraldi More articles by this author , Bernard GattegnoBernard Gattegno More articles by this author , Philippe ThibaultPhilippe Thibault More articles by this author , and Jean-Daniel SraerJean-Daniel Sraer More articles by this author View All Author Informationhttps://doi.org/10.1097/00005392-199707000-00012AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated the prevalence of renal cell carcinoma of the native kidneys in renal transplant recipients as well as possible risk factors. Materials and Methods: A total of 129 consecutive renal transplant recipients underwent ultrasound examination of the native kidneys as part of a routine evaluation. A record was made of acquired cystic kidney disease, defined as 3 cysts or more, and of suspicious masses. When a malignancy was suspected radical nephrectomy was performed. Results: The overall prevalence of renal cell carcinoma of the native kidney was 5 in 129 recipients (3.9%). All cancers were limited to the kidney. No significant relationship was detected between renal cell carcinoma occurrence and patient age, dialysis (when initiated, type and duration), transplantation, drug regimen or incidence of acquired cystic kidney disease. Conclusions: The risk of renal cell carcinoma, a clinically significant cancer, was approximately 100 times greater in our renal transplant patients than in the general population but no significant risk factor could be identified. Routine ultrasonography for early diagnosis in asymptomatic patients on immunosuppressive therapy is strongly recommended to improve prognosis. References 1 : Ten-year prospective study on the development of renal cell carcinoma in dialysis patients.. Amer. J. Kidney Dis.1990; 16: 452. Google Scholar 2 : Ultrasonic diagnosis of renal cell carcinoma in hemodialysis patients.. J. Urol.1994; 152: 846. Abstract, Google Scholar 3 : Renal cell carcinoma and acquired cystic kidney disease after renal transplantation.. Lancet1987; 1: 1030. Google Scholar 4 : Malignancies of the genito-urinary system following renal transplantation.. Brit. J. Urol.1995; 75: 572. Google Scholar 5 : Acquired cystic disease and renal adenocarcinoma following renal transplantation.. J. Urol.1994; 151: 129. Abstract, Google Scholar 6 : Metastatic renal cell carcinoma arising in a native kidney of a renal transplant recipient.. J. Urol.1994; 152: 943. Abstract, Google Scholar 7 : Prevalence of acquired cystic kidney disease and tumors in native kidneys of renal transplant recipients: a prospective US study.. Radiology1995; 195: 667. Google Scholar 8 : Incidence and properties of renal masses and asymptomatic renal cell carcinoma detected by abdominal ultrasonography.. J. Urol.1990; 144: 1097. Abstract, Google Scholar 9 : Renal cell carcinoma in patients with end-stage renal disease: a comparison of clinical significance in patients receiving hemodialysis and those with renal transplants.. Urology1994; 44: 497. Google Scholar 10 : Clinical course of malignancies in renal transplant recipients.. Cancer1993; 72: 2186. Google Scholar 11 : Primary kidney tumors before and after renal transplantation.. Transplantation1995; 59: 480. Google Scholar 12 : Renal cell carcinoma in a natural remaining kidney after two kidney transplantations. Case report.. Scand. J. Urol. Nephrol.1994; 28: 187. Google Scholar 13 : Acquired renal cystic disease in end-stage renal disease: an autopsy study of 155 cases.. Amer. J. Nephrol.1989; 9: 322. Google Scholar 14 : Acquired cystic disease of the kidney: a management dilemma.. J. Urol.1992; 147: 969. Abstract, Google Scholar 15 : Host renal cell carcinoma in kidney transplanted patient: ultrasonography screening study.. Transplant. Proc.1995; 27: 1786. Google Scholar From the Departments of Urology and Nephrology, Tenon Hospital, Paris, France.© 1997 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byLeveridge M, Musquera M, Evans A, Cardella C, Pei Y, Jewett M, Robinette M and Finelli A (2018) Renal Cell Carcinoma in the Native and Allograft Kidneys of Renal Transplant RecipientsJournal of Urology, VOL. 186, NO. 1, (219-223), Online publication date: 1-Jul-2011. Volume 158Issue 1July 1997Page: 42-44 Advertisement Copyright & Permissions© 1997 by American Urological Association, Inc.MetricsAuthor Information Jean-Dominique Doublet More articles by this author Marie-Noelle Peraldi More articles by this author Bernard Gattegno More articles by this author Philippe Thibault More articles by this author Jean-Daniel Sraer More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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