FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079185514> ?p ?o ?g. }

• W2079185514 endingPage "696" @default.
• W2079185514 startingPage "689" @default.
• W2079185514 abstract "We investigated the mechanism of host immune responses against two interferon-γ (IFN-γ) gene-transduced tumors, plasmacytoma MOPC104E(Muγ) and mammary cancer SC115(Kγ), which originally had weak immunogenicity. Both IFN-γ-producing tumor cells had reduced tumorigenicity and were rejected by syngeneic mice. The rejection was completely blocked by in vivo treatment with anti-CD8 or anti-IFN-γ monoclonal antibodies. While anti-CD4 monoclonal antibody also blocked the rejection of SC115(Kγ), it enhanced the initial tumor growth of MOPC104E(Muγ). Specific protection against subsequent challenge with the respective parental tumor cells was demonstrated in mice which rejected the IFN-γ-producing tumor cells. Cultured lymphocytes derived from immunized mouse spleens had cytotoxic T cell activity against parental tumor cells, as well as against cells that produced IFN-γ, These findings indicate that the antitumor effects are mediated by cytotoxic T cells and, partly, by helper T cells, and that locally secreted IFN-γ plays an important role in generating these effector cells." @default.
• W2079185514 created "2016-06-24" @default.
• W2079185514 creator A5005828577 @default.
• W2079185514 creator A5037752575 @default.
• W2079185514 creator A5050031455 @default.
• W2079185514 creator A5053446003 @default.
• W2079185514 creator A5079803799 @default.
• W2079185514 date "1993-06-01" @default.
• W2079185514 modified "2023-09-26" @default.
• W2079185514 title "Interferon-γ-producing Tumor Induces Host Tumor-specific T Cell Responses" @default.
• W2079185514 cites W1488558875 @default.
• W2079185514 cites W1500207531 @default.
• W2079185514 cites W1568528806 @default.
• W2079185514 cites W1572410922 @default.
• W2079185514 cites W1600662889 @default.
• W2079185514 cites W172251604 @default.
• W2079185514 cites W1753359669 @default.
• W2079185514 cites W1988637781 @default.
• W2079185514 cites W1989775015 @default.
• W2079185514 cites W1990668606 @default.
• W2079185514 cites W1994051663 @default.
• W2079185514 cites W2002323372 @default.
• W2079185514 cites W2007888049 @default.
• W2079185514 cites W2017596457 @default.
• W2079185514 cites W2023687151 @default.
• W2079185514 cites W2024654115 @default.
• W2079185514 cites W2027228821 @default.
• W2079185514 cites W2033394004 @default.
• W2079185514 cites W2033741683 @default.
• W2079185514 cites W2068032204 @default.
• W2079185514 cites W2069019236 @default.
• W2079185514 cites W2084906660 @default.
• W2079185514 cites W2091691801 @default.
• W2079185514 cites W2095171806 @default.
• W2079185514 cites W2104488113 @default.
• W2079185514 cites W2105998729 @default.
• W2079185514 cites W2116739229 @default.
• W2079185514 cites W2133159445 @default.
• W2079185514 cites W2134445712 @default.
• W2079185514 cites W2160809857 @default.
• W2079185514 cites W2165346890 @default.
• W2079185514 cites W2165662474 @default.
• W2079185514 cites W3100925801 @default.
• W2079185514 doi "https://doi.org/10.1111/j.1349-7006.1993.tb02030.x" @default.
• W2079185514 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5919329" @default.
• W2079185514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8340258" @default.
• W2079185514 hasPublicationYear "1993" @default.
• W2079185514 type Work @default.
• W2079185514 sameAs 2079185514 @default.
• W2079185514 citedByCount "11" @default.
• W2079185514 countsByYear W20791855142016 @default.
• W2079185514 crossrefType "journal-article" @default.
• W2079185514 hasAuthorship W2079185514A5005828577 @default.
• W2079185514 hasAuthorship W2079185514A5037752575 @default.
• W2079185514 hasAuthorship W2079185514A5050031455 @default.
• W2079185514 hasAuthorship W2079185514A5053446003 @default.
• W2079185514 hasAuthorship W2079185514A5079803799 @default.
• W2079185514 hasBestOaLocation W20791855141 @default.
• W2079185514 hasConcept C154317977 @default.
• W2079185514 hasConcept C159654299 @default.
• W2079185514 hasConcept C167672396 @default.
• W2079185514 hasConcept C202751555 @default.
• W2079185514 hasConcept C203014093 @default.
• W2079185514 hasConcept C2776178377 @default.
• W2079185514 hasConcept C2777701055 @default.
• W2079185514 hasConcept C2780868878 @default.
• W2079185514 hasConcept C502942594 @default.
• W2079185514 hasConcept C542903549 @default.
• W2079185514 hasConcept C55493867 @default.
• W2079185514 hasConcept C86803240 @default.
• W2079185514 hasConcept C8891405 @default.
• W2079185514 hasConceptScore W2079185514C154317977 @default.
• W2079185514 hasConceptScore W2079185514C159654299 @default.
• W2079185514 hasConceptScore W2079185514C167672396 @default.
• W2079185514 hasConceptScore W2079185514C202751555 @default.
• W2079185514 hasConceptScore W2079185514C203014093 @default.
• W2079185514 hasConceptScore W2079185514C2776178377 @default.
• W2079185514 hasConceptScore W2079185514C2777701055 @default.
• W2079185514 hasConceptScore W2079185514C2780868878 @default.
• W2079185514 hasConceptScore W2079185514C502942594 @default.
• W2079185514 hasConceptScore W2079185514C542903549 @default.
• W2079185514 hasConceptScore W2079185514C55493867 @default.
• W2079185514 hasConceptScore W2079185514C86803240 @default.
• W2079185514 hasConceptScore W2079185514C8891405 @default.
• W2079185514 hasIssue "6" @default.
• W2079185514 hasLocation W20791855141 @default.
• W2079185514 hasLocation W20791855142 @default.
• W2079185514 hasLocation W20791855143 @default.
• W2079185514 hasLocation W20791855144 @default.
• W2079185514 hasOpenAccess W2079185514 @default.
• W2079185514 hasPrimaryLocation W20791855141 @default.
• W2079185514 hasRelatedWork W1591820460 @default.
• W2079185514 hasRelatedWork W1899411185 @default.
• W2079185514 hasRelatedWork W195682249 @default.
• W2079185514 hasRelatedWork W1996150995 @default.
• W2079185514 hasRelatedWork W2327043232 @default.
• W2079185514 hasRelatedWork W2419379701 @default.
• W2079185514 hasRelatedWork W2984962695 @default.

• next