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- W2079186013 endingPage "3098" @default.
- W2079186013 startingPage "3079" @default.
- W2079186013 abstract "Interspecies comparisons of cDNA and mosaic milk protein genes have confirmed their high rate of evolution, but the overall gene organization has been conserved. The three Ca-sensitive casein genes, which share common motifs in the promoter region and contain similar sequences that encode signal peptide and multiple phosphorylation sites, probably derived from a common ancestor. alpha s1- and alpha s2-casein genes, divided into many small exons, undergo complex splicing, and the deleted caseins arise from exon skipping. The four bovine casein genes are clustered on 200 kb of chromosome 6. alpha-Lactalbumin and beta-lactoglobulin pseudogenes occur in ruminants. Study of the expression of native and modified milk protein genes in mammary cell lines and transgenic animals and DNA footprinting have shown the occurrence of important regulatory motifs in the proximal 5' flanking region, including one recognized by a specific mammary nuclear factor. Good stage- and tissue-specific expression has been obtained in transgenic animals with milk protein genes having less than a 3-kb 5' flanking region. Better knowledge of both the structure and function of milk protein genes, which has already allowed the use of powerful techniques for the rapid identification of alleles, offers the potential for the genetic modification of milk composition." @default.
- W2079186013 created "2016-06-24" @default.
- W2079186013 creator A5034060047 @default.
- W2079186013 creator A5063496576 @default.
- W2079186013 date "1993-10-01" @default.
- W2079186013 modified "2023-10-18" @default.
- W2079186013 title "Structure and Function of Milk Protein Genes" @default.
- W2079186013 cites W126526764 @default.
- W2079186013 cites W132416300 @default.
- W2079186013 cites W1512774372 @default.
- W2079186013 cites W1528283027 @default.
- W2079186013 cites W1528303930 @default.
- W2079186013 cites W1534369246 @default.
- W2079186013 cites W1566404299 @default.
- W2079186013 cites W1589525182 @default.
- W2079186013 cites W1591025537 @default.
- W2079186013 cites W1595583901 @default.
- W2079186013 cites W1597303621 @default.
- W2079186013 cites W1671211416 @default.
- W2079186013 cites W1706037773 @default.
- W2079186013 cites W1822511846 @default.
- W2079186013 cites W1882868104 @default.
- W2079186013 cites W1896222284 @default.
- W2079186013 cites W1904279590 @default.
- W2079186013 cites W1914857398 @default.
- W2079186013 cites W1918549573 @default.
- W2079186013 cites W1963524555 @default.
- W2079186013 cites W1964311222 @default.
- W2079186013 cites W1965359977 @default.
- W2079186013 cites W1965937576 @default.
- W2079186013 cites W1966961397 @default.
- W2079186013 cites W1968262678 @default.
- W2079186013 cites W1969591644 @default.
- W2079186013 cites W1971036936 @default.
- W2079186013 cites W1971186298 @default.
- W2079186013 cites W1971274557 @default.
- W2079186013 cites W1974130617 @default.
- W2079186013 cites W1974332756 @default.
- W2079186013 cites W1976215540 @default.
- W2079186013 cites W1977465224 @default.
- W2079186013 cites W1977805531 @default.
- W2079186013 cites W1978293233 @default.
- W2079186013 cites W1978713358 @default.
- W2079186013 cites W1980570794 @default.
- W2079186013 cites W1980732274 @default.
- W2079186013 cites W1982313934 @default.
- W2079186013 cites W1984311494 @default.
- W2079186013 cites W1986654939 @default.
- W2079186013 cites W1988987541 @default.
- W2079186013 cites W1989210771 @default.
- W2079186013 cites W1989259214 @default.
- W2079186013 cites W1989542617 @default.
- W2079186013 cites W1990989603 @default.
- W2079186013 cites W1991279507 @default.
- W2079186013 cites W1991298002 @default.
- W2079186013 cites W1995081777 @default.
- W2079186013 cites W1995210806 @default.
- W2079186013 cites W1999683386 @default.
- W2079186013 cites W1999694257 @default.
- W2079186013 cites W2001872369 @default.
- W2079186013 cites W2004113926 @default.
- W2079186013 cites W2008715822 @default.
- W2079186013 cites W2009420969 @default.
- W2079186013 cites W2014275179 @default.
- W2079186013 cites W2014738270 @default.
- W2079186013 cites W2020199669 @default.
- W2079186013 cites W2020466344 @default.
- W2079186013 cites W2020985893 @default.
- W2079186013 cites W2022399653 @default.
- W2079186013 cites W2023004121 @default.
- W2079186013 cites W2023684484 @default.
- W2079186013 cites W2026021060 @default.
- W2079186013 cites W2028107213 @default.
- W2079186013 cites W2028159021 @default.
- W2079186013 cites W2028970980 @default.
- W2079186013 cites W2030167715 @default.
- W2079186013 cites W2032391850 @default.
- W2079186013 cites W2033261080 @default.
- W2079186013 cites W2035238542 @default.
- W2079186013 cites W2035670990 @default.
- W2079186013 cites W2036096778 @default.
- W2079186013 cites W2036098607 @default.
- W2079186013 cites W2036510455 @default.
- W2079186013 cites W2036917468 @default.
- W2079186013 cites W2037818820 @default.
- W2079186013 cites W2039057191 @default.
- W2079186013 cites W2039463009 @default.
- W2079186013 cites W2039545168 @default.
- W2079186013 cites W2040851197 @default.
- W2079186013 cites W2041354540 @default.
- W2079186013 cites W2043108339 @default.
- W2079186013 cites W2046156438 @default.
- W2079186013 cites W2048916305 @default.
- W2079186013 cites W2051368655 @default.
- W2079186013 cites W2051863700 @default.
- W2079186013 cites W2052575270 @default.
- W2079186013 cites W2053759647 @default.
- W2079186013 cites W2054468292 @default.