Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079188947> ?p ?o ?g. }
- W2079188947 abstract "Metabolic syndrome (MetS) is composed of cardiovascular risk factors including insulin resistance, obesity, dyslipidemia, and hypertension. Most of the components of MetS have been linked to the development of neoplasm. The purpose of this study was to evaluate the relationship between individual components of MetS and colorectal adenoma.The study subjects were recruited from a pool of 4872 individuals who underwent a health check-up examination during the period January 2006 to May 2008. Each participant fulfilled a structured questionnaire. MetS was defined based on the America Heart Association and National Heart Lung Blood Institute criteria. Subjects with history of colon cancer, colon polyps, colitis, or prior colonic surgery were excluded.A total of 4122 subjects were included for final analysis (2367 men and 1755 women; mean age, 49.6 +/- 11.7 years). Of them, MetS was diagnosed in 708 men (29.9%) and in 367 women (20.9%). Among the patients with MetS, 34.6% had adenoma, 31.7% had hyperplastic polyps and 23.3% were polyp-free (p < 0.0001, Chi-square test). The adjusted OR for colorectal adenoma was significantly higher in the subjects with MetS (OR, 1.31, CI: 1.09-1.57). A stronger association between MetS and colorectal adenoma was found in men (OR:1.44, CI:1.16-1.80) than in women (OR:1.04, CI:0.74-1.46). The adjusted OR for adenoma increased as the number of MetS components increased (p for trend = 0.0001 ). When the individual components of MetS were analyzed separately, only central obesity (OR:1.36, CI:1.14-1.63), low HDL cholesterol levels (OR:1.30, CI:1.10-1.54) and high triglyceride levels (OR:1.26, CI:1.04-1.53) were independently associated with colorectal adenoma.Of the components of MetS analyzed in this study, central obesity and dyslipidemia are independent risk factors for colorectal adenoma. With regard to the prevention of colorectal neoplasm, life-style modification such as weight reduction is worthwhile." @default.
- W2079188947 created "2016-06-24" @default.
- W2079188947 creator A5012385557 @default.
- W2079188947 creator A5027015232 @default.
- W2079188947 creator A5028511972 @default.
- W2079188947 creator A5034323000 @default.
- W2079188947 creator A5046080598 @default.
- W2079188947 creator A5047580784 @default.
- W2079188947 creator A5054304598 @default.
- W2079188947 creator A5070686855 @default.
- W2079188947 creator A5076698507 @default.
- W2079188947 creator A5086801768 @default.
- W2079188947 date "2010-05-27" @default.
- W2079188947 modified "2023-10-16" @default.
- W2079188947 title "Central obesity and atherogenic dyslipidemia in metabolic syndrome are associated with increased risk for colorectal adenoma in a Chinese population" @default.
- W2079188947 cites W1514780253 @default.
- W2079188947 cites W1593442063 @default.
- W2079188947 cites W1979089787 @default.
- W2079188947 cites W2005756196 @default.
- W2079188947 cites W2057741556 @default.
- W2079188947 cites W2060409824 @default.
- W2079188947 cites W2062406653 @default.
- W2079188947 cites W2065534737 @default.
- W2079188947 cites W2066477484 @default.
- W2079188947 cites W2074587020 @default.
- W2079188947 cites W2103714496 @default.
- W2079188947 cites W2105677103 @default.
- W2079188947 cites W2105702970 @default.
- W2079188947 cites W2107863336 @default.
- W2079188947 cites W2130764919 @default.
- W2079188947 cites W2140165524 @default.
- W2079188947 cites W2141662760 @default.
- W2079188947 cites W2151152924 @default.
- W2079188947 cites W2156628154 @default.
- W2079188947 cites W2157305411 @default.
- W2079188947 cites W2167342921 @default.
- W2079188947 cites W2167726756 @default.
- W2079188947 doi "https://doi.org/10.1186/1471-230x-10-51" @default.
- W2079188947 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2894746" @default.
- W2079188947 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20507579" @default.
- W2079188947 hasPublicationYear "2010" @default.
- W2079188947 type Work @default.
- W2079188947 sameAs 2079188947 @default.
- W2079188947 citedByCount "101" @default.
- W2079188947 countsByYear W20791889472012 @default.
- W2079188947 countsByYear W20791889472013 @default.
- W2079188947 countsByYear W20791889472014 @default.
- W2079188947 countsByYear W20791889472015 @default.
- W2079188947 countsByYear W20791889472016 @default.
- W2079188947 countsByYear W20791889472017 @default.
- W2079188947 countsByYear W20791889472018 @default.
- W2079188947 countsByYear W20791889472019 @default.
- W2079188947 countsByYear W20791889472020 @default.
- W2079188947 countsByYear W20791889472021 @default.
- W2079188947 countsByYear W20791889472022 @default.
- W2079188947 countsByYear W20791889472023 @default.
- W2079188947 crossrefType "journal-article" @default.
- W2079188947 hasAuthorship W2079188947A5012385557 @default.
- W2079188947 hasAuthorship W2079188947A5027015232 @default.
- W2079188947 hasAuthorship W2079188947A5028511972 @default.
- W2079188947 hasAuthorship W2079188947A5034323000 @default.
- W2079188947 hasAuthorship W2079188947A5046080598 @default.
- W2079188947 hasAuthorship W2079188947A5047580784 @default.
- W2079188947 hasAuthorship W2079188947A5054304598 @default.
- W2079188947 hasAuthorship W2079188947A5070686855 @default.
- W2079188947 hasAuthorship W2079188947A5076698507 @default.
- W2079188947 hasAuthorship W2079188947A5086801768 @default.
- W2079188947 hasBestOaLocation W20791889471 @default.
- W2079188947 hasConcept C121608353 @default.
- W2079188947 hasConcept C126322002 @default.
- W2079188947 hasConcept C2776861080 @default.
- W2079188947 hasConcept C2777391703 @default.
- W2079188947 hasConcept C2777428134 @default.
- W2079188947 hasConcept C2777693730 @default.
- W2079188947 hasConcept C2778096610 @default.
- W2079188947 hasConcept C2780578515 @default.
- W2079188947 hasConcept C511355011 @default.
- W2079188947 hasConcept C526805850 @default.
- W2079188947 hasConcept C71924100 @default.
- W2079188947 hasConcept C90924648 @default.
- W2079188947 hasConceptScore W2079188947C121608353 @default.
- W2079188947 hasConceptScore W2079188947C126322002 @default.
- W2079188947 hasConceptScore W2079188947C2776861080 @default.
- W2079188947 hasConceptScore W2079188947C2777391703 @default.
- W2079188947 hasConceptScore W2079188947C2777428134 @default.
- W2079188947 hasConceptScore W2079188947C2777693730 @default.
- W2079188947 hasConceptScore W2079188947C2778096610 @default.
- W2079188947 hasConceptScore W2079188947C2780578515 @default.
- W2079188947 hasConceptScore W2079188947C511355011 @default.
- W2079188947 hasConceptScore W2079188947C526805850 @default.
- W2079188947 hasConceptScore W2079188947C71924100 @default.
- W2079188947 hasConceptScore W2079188947C90924648 @default.
- W2079188947 hasIssue "1" @default.
- W2079188947 hasLocation W20791889471 @default.
- W2079188947 hasLocation W20791889472 @default.
- W2079188947 hasLocation W20791889473 @default.
- W2079188947 hasLocation W20791889474 @default.
- W2079188947 hasLocation W20791889475 @default.
- W2079188947 hasOpenAccess W2079188947 @default.
- W2079188947 hasPrimaryLocation W20791889471 @default.