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- W2079207152 abstract "The brain is naturally considered as a network of interacting elements which, when functioning properly, produces an enormous range of dynamic, adaptable behavior. However, when elements of this network fail, pathological changes ensue, including epilepsy, one of the most common brain disorders. This review examines some aspects of cortical network organization that distinguish epileptic cortex from normal brain as well as the dynamics of network activity before and during seizures, focusing primarily on focal seizures. The review is organized around four phases of the seizure: the interictal period, onset, propagation, and termination. For each phase, the authors discuss the most common rhythmic characteristics of macroscopic brain voltage activity and outline the observed functional network features. Although the characteristics of functional networks that support the epileptic seizure remain an area of active research, the prevailing trends point to a complex set of network dynamics between, before, and during seizures." @default.
- W2079207152 created "2016-06-24" @default.
- W2079207152 creator A5031778533 @default.
- W2079207152 creator A5058048101 @default.
- W2079207152 date "2012-01-10" @default.
- W2079207152 modified "2023-10-16" @default.
- W2079207152 title "Epilepsy as a Disorder of Cortical Network Organization" @default.
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- W2079207152 doi "https://doi.org/10.1177/1073858411422754" @default.
- W2079207152 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3736575" @default.
- W2079207152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22235060" @default.
- W2079207152 hasPublicationYear "2012" @default.
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