Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079209659> ?p ?o ?g. }
- W2079209659 endingPage "155" @default.
- W2079209659 startingPage "143" @default.
- W2079209659 abstract "A dysfunction in the interaction between executive function and mood regulation has been proposed as the pathophysiology of depression. However, few studies have investigated the alteration in brain systems related to executive control over emotional distraction in depression. To address this issue, 19 patients with major depressive disorder (MDD) and 20 healthy controls were scanned using functional magnetic resonance imaging. Participants performed an emotional oddball task in which infrequently presented circle targets required detection while sad and neutral pictures were irrelevant novel distractors. Hemodynamic responses were compared for targets, sad distractors, and for targets that followed sad or neutral distractors (Target-after-Sad and Target-after-Neutral). Patients with MDD revealed attenuated activation overall to targets in executive brain regions. Behaviorally, MDD patients were slower in response to Target-after-Sad than Target-after-Neutra stimuli. Patients also revealed a reversed activation pattern from controls in response to this contrast in the left anterior cingulate, insula, right inferior frontal gyrus (IFG), and bilateral middle frontal gyrus. Those patients who engaged the right IFG more during Target-after-Neutral stimuli responded faster to targets, confirming a role of this region in coping with emotional distraction. The results provide direct evidence of an alteration in the neural systems that interplay cognition with mood in MDD." @default.
- W2079209659 created "2016-06-24" @default.
- W2079209659 creator A5006390763 @default.
- W2079209659 creator A5015972818 @default.
- W2079209659 creator A5021040823 @default.
- W2079209659 creator A5044990494 @default.
- W2079209659 creator A5067321338 @default.
- W2079209659 creator A5072414238 @default.
- W2079209659 creator A5078061801 @default.
- W2079209659 creator A5078447163 @default.
- W2079209659 date "2008-07-01" @default.
- W2079209659 modified "2023-10-16" @default.
- W2079209659 title "Prefrontal mechanisms for executive control over emotional distraction are altered in major depression" @default.
- W2079209659 cites W102868126 @default.
- W2079209659 cites W1571434348 @default.
- W2079209659 cites W1659864209 @default.
- W2079209659 cites W1665095741 @default.
- W2079209659 cites W1968626800 @default.
- W2079209659 cites W1968837585 @default.
- W2079209659 cites W1990494474 @default.
- W2079209659 cites W1991880588 @default.
- W2079209659 cites W1994426689 @default.
- W2079209659 cites W1997231957 @default.
- W2079209659 cites W1997245512 @default.
- W2079209659 cites W1999858294 @default.
- W2079209659 cites W2000998192 @default.
- W2079209659 cites W2006091191 @default.
- W2079209659 cites W2006192553 @default.
- W2079209659 cites W2022192636 @default.
- W2079209659 cites W2037629950 @default.
- W2079209659 cites W2037715202 @default.
- W2079209659 cites W2038068277 @default.
- W2079209659 cites W2040263710 @default.
- W2079209659 cites W2041293154 @default.
- W2079209659 cites W2043927532 @default.
- W2079209659 cites W2046078181 @default.
- W2079209659 cites W2050768782 @default.
- W2079209659 cites W2057046889 @default.
- W2079209659 cites W2058923243 @default.
- W2079209659 cites W2066186035 @default.
- W2079209659 cites W2068448466 @default.
- W2079209659 cites W2085647841 @default.
- W2079209659 cites W2087526026 @default.
- W2079209659 cites W2089030269 @default.
- W2079209659 cites W2091486663 @default.
- W2079209659 cites W2110290939 @default.
- W2079209659 cites W2111513387 @default.
- W2079209659 cites W2112011323 @default.
- W2079209659 cites W2114613490 @default.
- W2079209659 cites W2120182640 @default.
- W2079209659 cites W2125917054 @default.
- W2079209659 cites W2126485546 @default.
- W2079209659 cites W2132527498 @default.
- W2079209659 cites W2136256861 @default.
- W2079209659 cites W2144906195 @default.
- W2079209659 cites W2150261049 @default.
- W2079209659 cites W2150443804 @default.
- W2079209659 cites W2153566421 @default.
- W2079209659 cites W2154118084 @default.
- W2079209659 cites W2157217643 @default.
- W2079209659 cites W2159076163 @default.
- W2079209659 cites W2159763130 @default.
- W2079209659 cites W2163080134 @default.
- W2079209659 cites W2169605136 @default.
- W2079209659 cites W2171140194 @default.
- W2079209659 cites W4229580337 @default.
- W2079209659 cites W4229679565 @default.
- W2079209659 cites W4242605397 @default.
- W2079209659 cites W4254070537 @default.
- W2079209659 doi "https://doi.org/10.1016/j.pscychresns.2007.10.004" @default.
- W2079209659 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2553159" @default.
- W2079209659 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18455373" @default.
- W2079209659 hasPublicationYear "2008" @default.
- W2079209659 type Work @default.
- W2079209659 sameAs 2079209659 @default.
- W2079209659 citedByCount "174" @default.
- W2079209659 countsByYear W20792096592012 @default.
- W2079209659 countsByYear W20792096592013 @default.
- W2079209659 countsByYear W20792096592014 @default.
- W2079209659 countsByYear W20792096592015 @default.
- W2079209659 countsByYear W20792096592016 @default.
- W2079209659 countsByYear W20792096592017 @default.
- W2079209659 countsByYear W20792096592018 @default.
- W2079209659 countsByYear W20792096592019 @default.
- W2079209659 countsByYear W20792096592020 @default.
- W2079209659 countsByYear W20792096592021 @default.
- W2079209659 countsByYear W20792096592022 @default.
- W2079209659 countsByYear W20792096592023 @default.
- W2079209659 crossrefType "journal-article" @default.
- W2079209659 hasAuthorship W2079209659A5006390763 @default.
- W2079209659 hasAuthorship W2079209659A5015972818 @default.
- W2079209659 hasAuthorship W2079209659A5021040823 @default.
- W2079209659 hasAuthorship W2079209659A5044990494 @default.
- W2079209659 hasAuthorship W2079209659A5067321338 @default.
- W2079209659 hasAuthorship W2079209659A5072414238 @default.
- W2079209659 hasAuthorship W2079209659A5078061801 @default.
- W2079209659 hasAuthorship W2079209659A5078447163 @default.
- W2079209659 hasBestOaLocation W20792096592 @default.