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- W2079216945 abstract "The study reported here is one of several in which we evaluated the effects of benzodiazepine tranquilizer on persons in an anxiety-inducing situation—outpatient dentistry. The study had three purposes: (1) to see whether a benzodiazepine tranquilizer, chlordiazepoxide, would reduce anxiety in patients undergoing a standard dental procedure; (2) to see whether the anxiety reduction would be greater in patients predicted to be highly anxious during dental procedures as contrasted with those predicted to be minimally anxious; (3) to compare chlordiazepoxide and phenobarbital on criteria of anxiety reduction and the presence of side effects such as sedation. Our previous studies using diazepam in highly anxious dental patients suggested that it was somewhat more effective than placebo, but not greatly so.1 In the present study we added a group of patients who were not particularly anxious about dentistry, predicting that they would have essentially no antianxiety response to the medication. The design of this study was to choose 6 patients scoring high on fear of dental procedures and 6 scoring low. They were given chlordiazepoxide, phenobarbital, or placebo in a three-session repeated-measures design. The design therefore consisted of two levels of patient dental fear and three medications." @default.
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- W2079216945 date "1975-01-01" @default.
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- W2079216945 title "Chlordiazepoxide and phenobarbital in a model anxiety-inducing situation" @default.
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- W2079216945 doi "https://doi.org/10.1016/0010-440x(75)90026-7" @default.
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