Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079217524> ?p ?o ?g. }
- W2079217524 abstract "Hyperhomocysteinemia is considered as a risk factor for cardiovascular diseases. Usually, an inverse relationship exists between homocysteine and folate levels, and supplementation with folate lowers homocysteine concentrations in patients. Therefore, hyperhomocysteinemia is mainly ascribed to the insufficient dietary intake of folate. Hyperhomocysteinemia has also been observed in infections and inflammatory diseases. Oxidative stress appears to be involved in the pathogenesis of these disorders, and associations have been found between homocysteine and e.g., neopterin concentration. Increased neopterin concentration indicates immune system activation and also allows an estimate of thus elicited oxidative stress. It may be relevant that the active cofactor, tetrahydrofolate, is very susceptible to oxidation. Immunologically induced oxidative stress could lead to folate depletion resulting in hyperhomocysteinemia. Thus, hyperhomocysteinemia in patients can be considered as an indirect consequence of hyperconsumption of antioxidant vitamins during prolonged states of immune activation." @default.
- W2079217524 created "2016-06-24" @default.
- W2079217524 creator A5012917581 @default.
- W2079217524 creator A5029922541 @default.
- W2079217524 creator A5051503017 @default.
- W2079217524 creator A5068067886 @default.
- W2079217524 creator A5071476152 @default.
- W2079217524 creator A5081156604 @default.
- W2079217524 date "2001-01-31" @default.
- W2079217524 modified "2023-10-16" @default.
- W2079217524 title "Is Hyperhomocysteinemia due to the Oxidative Depletion of Folate rather than to Insufficient Dietary Intake?" @default.
- W2079217524 cites W1869368673 @default.
- W2079217524 cites W1977841860 @default.
- W2079217524 cites W1983722372 @default.
- W2079217524 cites W1990376420 @default.
- W2079217524 cites W1997067835 @default.
- W2079217524 cites W2020126595 @default.
- W2079217524 cites W2027665192 @default.
- W2079217524 cites W2028793368 @default.
- W2079217524 cites W2038463122 @default.
- W2079217524 cites W2042641359 @default.
- W2079217524 cites W2048748461 @default.
- W2079217524 cites W2053130249 @default.
- W2079217524 cites W2053447410 @default.
- W2079217524 cites W2059913943 @default.
- W2079217524 cites W2089748644 @default.
- W2079217524 cites W2100419387 @default.
- W2079217524 cites W2156255102 @default.
- W2079217524 cites W2321244645 @default.
- W2079217524 cites W2332958520 @default.
- W2079217524 cites W2409995614 @default.
- W2079217524 cites W4256578596 @default.
- W2079217524 doi "https://doi.org/10.1515/cclm.2001.113" @default.
- W2079217524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11592434" @default.
- W2079217524 hasPublicationYear "2001" @default.
- W2079217524 type Work @default.
- W2079217524 sameAs 2079217524 @default.
- W2079217524 citedByCount "90" @default.
- W2079217524 countsByYear W20792175242012 @default.
- W2079217524 countsByYear W20792175242013 @default.
- W2079217524 countsByYear W20792175242014 @default.
- W2079217524 countsByYear W20792175242015 @default.
- W2079217524 countsByYear W20792175242016 @default.
- W2079217524 countsByYear W20792175242017 @default.
- W2079217524 countsByYear W20792175242019 @default.
- W2079217524 countsByYear W20792175242020 @default.
- W2079217524 countsByYear W20792175242021 @default.
- W2079217524 countsByYear W20792175242023 @default.
- W2079217524 crossrefType "journal-article" @default.
- W2079217524 hasAuthorship W2079217524A5012917581 @default.
- W2079217524 hasAuthorship W2079217524A5029922541 @default.
- W2079217524 hasAuthorship W2079217524A5051503017 @default.
- W2079217524 hasAuthorship W2079217524A5068067886 @default.
- W2079217524 hasAuthorship W2079217524A5071476152 @default.
- W2079217524 hasAuthorship W2079217524A5081156604 @default.
- W2079217524 hasConcept C126322002 @default.
- W2079217524 hasConcept C134018914 @default.
- W2079217524 hasConcept C185592680 @default.
- W2079217524 hasConcept C203014093 @default.
- W2079217524 hasConcept C2776145790 @default.
- W2079217524 hasConcept C2776151105 @default.
- W2079217524 hasConcept C2776523773 @default.
- W2079217524 hasConcept C2776603314 @default.
- W2079217524 hasConcept C2777090595 @default.
- W2079217524 hasConcept C2777451243 @default.
- W2079217524 hasConcept C2777622882 @default.
- W2079217524 hasConcept C2780942790 @default.
- W2079217524 hasConcept C3020471959 @default.
- W2079217524 hasConcept C519581460 @default.
- W2079217524 hasConcept C55493867 @default.
- W2079217524 hasConcept C57600042 @default.
- W2079217524 hasConcept C71924100 @default.
- W2079217524 hasConceptScore W2079217524C126322002 @default.
- W2079217524 hasConceptScore W2079217524C134018914 @default.
- W2079217524 hasConceptScore W2079217524C185592680 @default.
- W2079217524 hasConceptScore W2079217524C203014093 @default.
- W2079217524 hasConceptScore W2079217524C2776145790 @default.
- W2079217524 hasConceptScore W2079217524C2776151105 @default.
- W2079217524 hasConceptScore W2079217524C2776523773 @default.
- W2079217524 hasConceptScore W2079217524C2776603314 @default.
- W2079217524 hasConceptScore W2079217524C2777090595 @default.
- W2079217524 hasConceptScore W2079217524C2777451243 @default.
- W2079217524 hasConceptScore W2079217524C2777622882 @default.
- W2079217524 hasConceptScore W2079217524C2780942790 @default.
- W2079217524 hasConceptScore W2079217524C3020471959 @default.
- W2079217524 hasConceptScore W2079217524C519581460 @default.
- W2079217524 hasConceptScore W2079217524C55493867 @default.
- W2079217524 hasConceptScore W2079217524C57600042 @default.
- W2079217524 hasConceptScore W2079217524C71924100 @default.
- W2079217524 hasIssue "8" @default.
- W2079217524 hasLocation W20792175241 @default.
- W2079217524 hasLocation W20792175242 @default.
- W2079217524 hasOpenAccess W2079217524 @default.
- W2079217524 hasPrimaryLocation W20792175241 @default.
- W2079217524 hasRelatedWork W1598461491 @default.
- W2079217524 hasRelatedWork W1981219971 @default.
- W2079217524 hasRelatedWork W1996283706 @default.
- W2079217524 hasRelatedWork W2039925094 @default.
- W2079217524 hasRelatedWork W2073380334 @default.
- W2079217524 hasRelatedWork W2081730997 @default.