Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079218706> ?p ?o ?g. }
- W2079218706 endingPage "1927.e1" @default.
- W2079218706 startingPage "1922" @default.
- W2079218706 abstract "ObjectiveTo evaluate the effect of hypothalamic/pituitary radiation (HPT RT) dose on the occurrence of first pregnancy.DesignRetrospective cohort study of childhood cancer 5-year survivors (CCS) diagnosed between 1970 and 1986 before 21 years of age at one of 26 North American pediatric cancer treatment centers.SettingSelf-administered questionnaire.Patient(s)A total of 3,619 female CCS who participated in the Childhood Cancer Survivor Study and received no or scatter (≤0.1 Gy) radiation to the ovaries and 2,081 female siblings (Sibs) of the participants.Intervention(s)None.Main Outcome Measure(s)Self-reported pregnancy events.Result(s)As a group, CCS were as likely to report being pregnant as Sibs (hazard ratio 1.07, 95% confidence interval 0.97–1.19). Multivariable models showed a significant decrease in the risk of pregnancy with HPT RT doses ≥22 Gy compared with those CCS receiving no HPT RT.Conclusion(s)These results support the hypothesis that exposures of 22–27 Gy HPT RT may be a contributing factor to infertility among female CCS. To evaluate the effect of hypothalamic/pituitary radiation (HPT RT) dose on the occurrence of first pregnancy. Retrospective cohort study of childhood cancer 5-year survivors (CCS) diagnosed between 1970 and 1986 before 21 years of age at one of 26 North American pediatric cancer treatment centers. Self-administered questionnaire. A total of 3,619 female CCS who participated in the Childhood Cancer Survivor Study and received no or scatter (≤0.1 Gy) radiation to the ovaries and 2,081 female siblings (Sibs) of the participants. None. Self-reported pregnancy events. As a group, CCS were as likely to report being pregnant as Sibs (hazard ratio 1.07, 95% confidence interval 0.97–1.19). Multivariable models showed a significant decrease in the risk of pregnancy with HPT RT doses ≥22 Gy compared with those CCS receiving no HPT RT. These results support the hypothesis that exposures of 22–27 Gy HPT RT may be a contributing factor to infertility among female CCS." @default.
- W2079218706 created "2016-06-24" @default.
- W2079218706 creator A5006774665 @default.
- W2079218706 creator A5012975912 @default.
- W2079218706 creator A5046016361 @default.
- W2079218706 creator A5057352179 @default.
- W2079218706 creator A5059262359 @default.
- W2079218706 creator A5063077038 @default.
- W2079218706 creator A5067443773 @default.
- W2079218706 creator A5079179135 @default.
- W2079218706 creator A5090006346 @default.
- W2079218706 date "2011-05-01" @default.
- W2079218706 modified "2023-10-17" @default.
- W2079218706 title "Decreased fertility among female childhood cancer survivors who received 22–27 Gy hypothalamic/pituitary irradiation: a report from the Childhood Cancer Survivor Study" @default.
- W2079218706 cites W1967818337 @default.
- W2079218706 cites W1970161747 @default.
- W2079218706 cites W1977198369 @default.
- W2079218706 cites W1984267845 @default.
- W2079218706 cites W2028694015 @default.
- W2079218706 cites W2040641217 @default.
- W2079218706 cites W2041344443 @default.
- W2079218706 cites W2058217833 @default.
- W2079218706 cites W2084669890 @default.
- W2079218706 cites W2088377728 @default.
- W2079218706 cites W2101807916 @default.
- W2079218706 cites W2102585911 @default.
- W2079218706 cites W2106782951 @default.
- W2079218706 cites W2124156734 @default.
- W2079218706 cites W2128975535 @default.
- W2079218706 cites W2129260593 @default.
- W2079218706 cites W2134865515 @default.
- W2079218706 cites W2135862919 @default.
- W2079218706 cites W2138210947 @default.
- W2079218706 cites W2140338619 @default.
- W2079218706 cites W2155059218 @default.
- W2079218706 cites W2162039240 @default.
- W2079218706 cites W2163726181 @default.
- W2079218706 cites W2167852330 @default.
- W2079218706 cites W2171937346 @default.
- W2079218706 cites W2322561651 @default.
- W2079218706 doi "https://doi.org/10.1016/j.fertnstert.2011.02.002" @default.
- W2079218706 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3080448" @default.
- W2079218706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21376314" @default.
- W2079218706 hasPublicationYear "2011" @default.
- W2079218706 type Work @default.
- W2079218706 sameAs 2079218706 @default.
- W2079218706 citedByCount "40" @default.
- W2079218706 countsByYear W20792187062012 @default.
- W2079218706 countsByYear W20792187062013 @default.
- W2079218706 countsByYear W20792187062014 @default.
- W2079218706 countsByYear W20792187062015 @default.
- W2079218706 countsByYear W20792187062016 @default.
- W2079218706 countsByYear W20792187062017 @default.
- W2079218706 countsByYear W20792187062018 @default.
- W2079218706 countsByYear W20792187062019 @default.
- W2079218706 countsByYear W20792187062020 @default.
- W2079218706 countsByYear W20792187062021 @default.
- W2079218706 countsByYear W20792187062023 @default.
- W2079218706 crossrefType "journal-article" @default.
- W2079218706 hasAuthorship W2079218706A5006774665 @default.
- W2079218706 hasAuthorship W2079218706A5012975912 @default.
- W2079218706 hasAuthorship W2079218706A5046016361 @default.
- W2079218706 hasAuthorship W2079218706A5057352179 @default.
- W2079218706 hasAuthorship W2079218706A5059262359 @default.
- W2079218706 hasAuthorship W2079218706A5063077038 @default.
- W2079218706 hasAuthorship W2079218706A5067443773 @default.
- W2079218706 hasAuthorship W2079218706A5079179135 @default.
- W2079218706 hasAuthorship W2079218706A5090006346 @default.
- W2079218706 hasBestOaLocation W20792187061 @default.
- W2079218706 hasConcept C121608353 @default.
- W2079218706 hasConcept C126322002 @default.
- W2079218706 hasConcept C131872663 @default.
- W2079218706 hasConcept C167135981 @default.
- W2079218706 hasConcept C187212893 @default.
- W2079218706 hasConcept C201903717 @default.
- W2079218706 hasConcept C207103383 @default.
- W2079218706 hasConcept C2777688143 @default.
- W2079218706 hasConcept C2777904497 @default.
- W2079218706 hasConcept C2779234561 @default.
- W2079218706 hasConcept C2908647359 @default.
- W2079218706 hasConcept C29456083 @default.
- W2079218706 hasConcept C2992894027 @default.
- W2079218706 hasConcept C44249647 @default.
- W2079218706 hasConcept C509974204 @default.
- W2079218706 hasConcept C518429986 @default.
- W2079218706 hasConcept C54355233 @default.
- W2079218706 hasConcept C71924100 @default.
- W2079218706 hasConcept C72563966 @default.
- W2079218706 hasConcept C86803240 @default.
- W2079218706 hasConcept C99454951 @default.
- W2079218706 hasConceptScore W2079218706C121608353 @default.
- W2079218706 hasConceptScore W2079218706C126322002 @default.
- W2079218706 hasConceptScore W2079218706C131872663 @default.
- W2079218706 hasConceptScore W2079218706C167135981 @default.
- W2079218706 hasConceptScore W2079218706C187212893 @default.
- W2079218706 hasConceptScore W2079218706C201903717 @default.
- W2079218706 hasConceptScore W2079218706C207103383 @default.
- W2079218706 hasConceptScore W2079218706C2777688143 @default.