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• W2079220907 abstract "The adipose tissue hormone, leptin, and the neuropeptide glucagon‐like peptide‐1 (7–36) amide (GLP‐1) both reduce food intake and body weight in rodents. Using dual in situ hybridization, long isoform leptin receptor (OB‐Rb) was localized to GLP‐1 neurons originating in the nucleus of the solitary tract. ICV injection of the specific GLP‐1 receptor antagonist, exendin(9–39), at the onset of dark phase, did not affect feeding in saline pre‐treated controls, but blocked the reduction in food intake and body weight of leptin pre‐treated rats. These findings suggest that GLP‐1 neurons are a potential target for leptin in its control of feeding." @default.
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• W2079220907 date "1997-09-29" @default.
• W2079220907 modified "2023-10-18" @default.
• W2079220907 title "Leptin interacts with glucagon‐like peptide‐1 neurons to reduce food intake and body weight in rodents" @default.
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• W2079220907 doi "https://doi.org/10.1016/s0014-5793(97)01103-4" @default.
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