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- W2079228057 abstract "Oxidative and inflammatory stress have been implicated as major contributors to the aging process. Dietary Ca reduced both factors in short-term interventions, while milk exerted a greater effect than supplemental Ca. In this work, we examined the effects of life-long supplemental and dairy calcium on lifespan and life-span related biomarkers in aP2-agouti transgenic (model of diet-induced obesity) and wild-type mice fed obesigenic diets until their death. These data demonstrate that dairy Ca exerts sustained effects resulting in attenuated adiposity, protection against age-related muscle loss and reduction of oxidative and inflammatory stress in both mouse strains. Although these effects did not alter maximum lifespan, they did suppress early mortality in wild-type mice, but not in aP2-agouti transgenic mice." @default.
- W2079228057 created "2016-06-24" @default.
- W2079228057 creator A5044741094 @default.
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- W2079228057 date "2009-08-14" @default.
- W2079228057 modified "2023-09-25" @default.
- W2079228057 title "Dietary Calcium and Dairy Modulation of Oxidative Stress and Mortality in aP2-Agouti and Wild-type Mice" @default.
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- W2079228057 doi "https://doi.org/10.3390/nu1010050" @default.
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