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- W2079248862 abstract "Annual dobutamine stress echocardiography (DSE) is used to detect cardiac allograft vasculopathy in heart transplant (HTX) recipients. Atropine is commonly used in non-transplant patients to increase the sensitivity of DSE by achieving the target heart rate (THR=85% of 220 – patient’s age). Orthotopic HTX completely denervates the donor’s heart, with little evidence to suggest parasympathetic reinnervation. As such, the efficacy of atropine as a chronotropic agent in HTX patients undergoing DSE is unknown. A retrospective review from August 2008 to February 2011 yielded 173 consecutive, individual HTX patients (56.5± 13 years; time since HTX 9.5± 5 years) after excluding seven patients on negatively chronotropic medication within 48 hours prior to DSE. Standard protocol dobutamine was commenced at 5mcg/kg/min. If THR was not attained at 50mcg/kg/min, a bolus of maximal 1200mcg atropine was given. 123 p p 6 i v y y p" @default.
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- W2079248862 date "2011-01-01" @default.
- W2079248862 modified "2023-09-28" @default.
- W2079248862 title "Effectiveness of Atropine as a Chronotropic Adjunct in Cardiac Transplant Recipients Undergoing Dobutamine Stress Echocardiography" @default.
- W2079248862 doi "https://doi.org/10.1016/j.hlc.2011.05.429" @default.
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