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• W2079255220 abstract "Article1 February 1965Cardiac PacemakingII. Physiological StudiesWILLIAM L. WINTERS JR., M.D., F.A.C.P., R. ROBERT TYSON, M.D., FRANK BARRERA, M.D., LOUIS A. SOLOFF, M.D., F.A.C.P.WILLIAM L. WINTERS JR., M.D., F.A.C.P.Search for more papers by this author, R. ROBERT TYSON, M.D.Search for more papers by this author, FRANK BARRERA, M.D.Search for more papers by this author, LOUIS A. SOLOFF, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-2-220 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA companion report documents the clinical course of 20 patients with Stokes-Adams seizures who have been treated with various types of electronic cardiac pacemakers (1). This group includes 13 patients in whom internal implantable mercury battery powered pacemakers with a fixed ventricular rate were employed.*Six patients in this group volunteered to return for physiological studies by cardiac catheterization technique. Other reports have dealt with the hemodynamic consequences of variable rate pacemakers at rest and during exercise in what might be termed acute observations in that the studies were performed at different cardiac rates over a short period of time—usually...References1. WINTERSTYSONSOLOFF WLRRLA: Cardiac pacemaking: I. Clinical experience. Ann. Intern. Med. 62: 2, 000. Google Scholar2. BEVEGARD S: Observations on the effect of varying ventricular rate on the circulation at rest and during exercise in two patients with an artificial pacemaker. Acta Med. Scand. 172: 615, 1962. CrossrefMedlineGoogle Scholar3. BENCHIMOLLIDIMONDVOTHROLAND AYEGRBAS: Effect of heart rate, exercise and nitroglycerin on the cardiac dynamics in complete heart block. Circulation 28: 510, 1963. CrossrefMedlineGoogle Scholar4. LASRYBENCHIMOLBARONOFSKYCARVALKO JEAIDFR: Cardiovascular hemodynamics and the internally placed cardiac catheter. Amer. J. Cardiol. 11: 399, 1963. CrossrefGoogle Scholar5. HAUPTMYERSDOXLYBIRKHEAD GJRNJWNC: Implanted cardiac pacemakers of variable frequency. Hemodynamic studies of two patients. JAMA 185: 123, 1963. CrossrefMedlineGoogle Scholar6. SAMETJACOBSBERNSTEINSHANE PWWHR: Hemodynamic sequelae of idioventricular pacemaking in complete heart block. Amer. J. Cardiol. 11: 594, 1963. CrossrefMedlineGoogle Scholar7. MILLERGLEASONWHALENMORRISMCINTOSH DEWLREJJHD: Effect of ventricular rate on the cardiac output in the dog with chronic heart block. Circ. Res. 10: 658, 1962. CrossrefMedlineGoogle Scholar8. 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SELZERWILLETTMCCAUGHEYFEICHTMEIR AFMDJTV: Uses of cardiac catheterization in acquired heart disease. New Eng. J. Med. 257: 66, 121, 1957. CrossrefMedlineGoogle Scholar13. COURNANDRILEYBREEDBALDWINRICHARDS ARLESEDDW: Measurement of cardiac output in man using the technique of catheterization of the right auricle or ventricle. J. Clin. Invest. 24: 106, 1944. CrossrefGoogle Scholar14. SMITHWIKLERFOX WWSAC: Hemodynamic studies of patients with myocardial infarction. Circulation 9: 352, 1954. CrossrefMedlineGoogle Scholar15. BRANDFONBRENERLANDOWNESHOCK MMNW: Changes in cardiac output with age. Circulation 12: 557, 1955. CrossrefMedlineGoogle Scholar16. STACKRADERSOBOLFARBEREICHNA MFBBJSJLW: Cardiovascular hemodynamic functions in complete heart block and the effect of isopropyl norepinephrine. Circulation 12: 526, 1958. CrossrefGoogle Scholar17. DONALDBISHOPCUMMINGWADE KWJMGOL: The effect of exercise on the cardiac output and circulatory dynamics of normal subjects. Clin. Sci. 14: 37, 1955. MedlineGoogle Scholar18. SELZERMCCAUGHEY ADJ: Hemodynamic patterns in chronic cardiac failure. Amer. J. Med. 28: 337, 1960. CrossrefMedlineGoogle Scholar19. HARVEYSMITHPARKERFERRER RMWMJOMI: The response of the abnormal heart to exercise. Circulation 26: 341, 1962. CrossrefMedlineGoogle Scholar20. SANCETTARAKITA SML: Response of pulmonary artery pressure and total pulmonary resistance of untrained convalescent man to prolonged mild steady state exercise. J. Clin. Invest. 36: 1138, 1957. CrossrefMedlineGoogle Scholar21. SLONIMRAVINBALCHUMDRESSLER NBAOJSH: The effect of mild exercise in the supine positions on the pulmonary arterial pressure of five normal human subjects. J. Clin. Invest. 33: 1022, 1954. CrossrefMedlineGoogle Scholar22. DEXTERWHITTENBERGERHAYNESGOODALEGORLINSAWYER LJLFWWTRCG: Effect of exercise on circulatory dynamics of normal individuals. J. Appl. Physiol. 3: 439, 1951. CrossrefMedlineGoogle Scholar23. BEVEGARDHOLMGREJONSSON SAB: The effect of body position on the circulation at rest and during exercise, with special reference to the influence on stroke volume. Acta Physiol. Scand. 49: 279, 1960. CrossrefMedlineGoogle Scholar24. RUSHMER RF: Constancy of stroke volume in ventricular responses to exertion. Amer. J. Physiol. 196: 745, 1959. CrossrefMedlineGoogle Scholar25. WARNERTORONTO HRAF: Regulation of cardiac output through stroke volume. Circ. Res. 8: 549, 1960. CrossrefMedlineGoogle Scholar26. SHEPHERDWANGMARSHALL JTYRJ: Relative contribution of changes in heart rate and stroke volume to the increase in cardiac output in dogs during exercise. Physiologist 2: 105, 1959. Google Scholar27. LEVINENEILLWAGMANKRASNOWGORLIN HJWARJNR: The effect of exercise on mean left ventricular ejection rate in man. J. Clin. Invest. 41: 1050, 1962. CrossrefMedlineGoogle Scholar28. IKKOSHANSEN DJS: Response to exercise in congenital complete atrioventricular block. Circulation 22: 583, 1960. CrossrefMedlineGoogle Scholar29. BICKELMANNLIPPSCHUTZWEINSTEIN AGEJL: The response of the normal and the abnormal heart to exercise. Circulation 28: 238, 1963. CrossrefMedlineGoogle Scholar30. HECHTLANGE HHRL: The hemodynamic consequences of atrial fibrillation. Mod. Cone. Cardiovasc. Dis. 25: 351, 1956. MedlineGoogle Scholar31. HECHTOSHERSAMUELS HHWJAJ: Cardiovascular adjustments in subjects with organic heart disease before and after conversion of atrial fibrillation to normal sinus rhythm. J. Clin. Invest. 30: 647, 1951. Google Scholar32. KORYMENEELY RCGR: Cardiac output in auricular fibrillation with observations on the effect of conversion to normal sinus rhythm. J. Clin. Invest. 30: 653, 1951. Google Scholar33. WIGGERSKATZ CJLN: Contour of ventricular volume curves under different conditions. Amer. J. Physiol. 58: 439, 1921. CrossrefGoogle Scholar34. LINDWEGELIUSLICHTENSTEIN JCH: The dynamics of the heart in complete A-V block, an angiocardiographic study. Circulation 10: 195, 1954. CrossrefMedlineGoogle Scholar35. JOCHIM K: The contribution of the auricles to ventricular filling in complete heart block. Amer. J. Physiol. 122: 639, 1938. CrossrefGoogle Scholar36. STEPHENSONEDWARDSJOLLYSCOTT EEWHPCHW: Physiologic P-wave cardiac stimulator. J. Thorac. Cardiov. Surg. 38: 604, 1959. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, PennsylvaniaFrom the Departments of Medicine and Surgery, Temple University Medical Center, Philadelphia, Pa.This study was supported in part by Grant HE 06313 from the U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to William L. Winters, Jr., M.D., Temple University Hospital, 3401 N. Broad St., Philadelphia, Pa. 19140.*Medtronics Inc., Minneapolis, Minn. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHemodynamics of the Paced HeartAntibradykarde Stimulation: Prognose, Hämodynamik, IndikationenCardiac Output Versus Pacing Rate at Rest and with Exercise in Dogs with AV BlockDeleterious Effects of Cardiac Pacing in a Patient with Mitral InsufficiencyThe Stokes-Adams syndromeDie Elektrotherapie der Rhythmusstörungen des HerzensDifferentialtherapie mit verschiedenen HerzschrittmachertypenCardiac Hemodynamics During Stimulation of the Right Atrium, Right Ventricle, and Left Ventricle in Normal and Abnormal HeartsCardiac functions during electrical stimulation of the heart 1 February 1965Volume 62, Issue 2Page: 220-230KeywordsCardiac surgeryCatheterizationElectrophysiological techniquesEpileptic seizuresExerciseHeart rateHemodynamicsMedical servicesPacemakers Issue Published: 1 February 1965 PDF downloadLoading ..." @default.
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