Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079262414> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2079262414 endingPage "136" @default.
- W2079262414 startingPage "133" @default.
- W2079262414 abstract "The metabolism of 75Se-labeled SeO32− and its conversion by intact rat erythrocytes in vitro to a form which complexes with Cd and plasma proteins were studied. By utilizing both excess SeO32− and N-ethylmaleimide to lower erythrocyte reduced glutathione (GSH) concentrations, it was shown that the uptake and metabolism of SeO32− were GSH-dependent, the probable intermediate being glutathione selenotrisulfide (GSSeSG). Secondary release of selenium by rat erythrocytes had no relation to the erythrocyte transport of oxidized glutathione (GSSG). While fluoride depressed and chromate increased GSSG transport, chromate, a glutathione reductase inhibitor, decreased selenium release. This release appeared to be secondary to a reaction catalyzed by glutathione reductase. The similarity of I50 values for chromate's inhibition of glutathione reductase and for the inhibition of selenium release further suggested a relationship between these two events. H2Se or a similar product of GSSeSG reduction is proposed to be the active product of SeO32− metabolism by rat erythrocytes. By use of gel-filtration and ion-exchange methods it was noted that the incubation of H2Se with cadmium and plasma produced a Cd–Se complex indistinguishable from that produced by incubation of Cd, SeO32−, plasma, and erythrocytes in vitro, or that noted following the administration of Cd and SeO3 in vivo. A mechanism whereby the tissue distribution and toxicity of cadmium are altered by selenium is suggested." @default.
- W2079262414 created "2016-06-24" @default.
- W2079262414 creator A5025119335 @default.
- W2079262414 creator A5072334153 @default.
- W2079262414 date "1978-08-01" @default.
- W2079262414 modified "2023-10-14" @default.
- W2079262414 title "Interaction between cadmium and selenium in rat plasma" @default.
- W2079262414 cites W1950160780 @default.
- W2079262414 cites W1969776684 @default.
- W2079262414 cites W1974695623 @default.
- W2079262414 cites W1977992601 @default.
- W2079262414 cites W2041655473 @default.
- W2079262414 cites W2053208311 @default.
- W2079262414 cites W2055924302 @default.
- W2079262414 cites W2058919513 @default.
- W2079262414 cites W2123652464 @default.
- W2079262414 cites W2126393573 @default.
- W2079262414 cites W2318162403 @default.
- W2079262414 cites W2408609284 @default.
- W2079262414 cites W2418438435 @default.
- W2079262414 cites W2470237589 @default.
- W2079262414 doi "https://doi.org/10.1289/ehp.7825133" @default.
- W2079262414 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1637195" @default.
- W2079262414 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/720299" @default.
- W2079262414 hasPublicationYear "1978" @default.
- W2079262414 type Work @default.
- W2079262414 sameAs 2079262414 @default.
- W2079262414 citedByCount "28" @default.
- W2079262414 countsByYear W20792624142013 @default.
- W2079262414 countsByYear W20792624142015 @default.
- W2079262414 countsByYear W20792624142022 @default.
- W2079262414 crossrefType "journal-article" @default.
- W2079262414 hasAuthorship W2079262414A5025119335 @default.
- W2079262414 hasAuthorship W2079262414A5072334153 @default.
- W2079262414 hasBestOaLocation W20792624141 @default.
- W2079262414 hasConcept C150903083 @default.
- W2079262414 hasConcept C165069038 @default.
- W2079262414 hasConcept C178790620 @default.
- W2079262414 hasConcept C181199279 @default.
- W2079262414 hasConcept C185592680 @default.
- W2079262414 hasConcept C207001950 @default.
- W2079262414 hasConcept C2778760513 @default.
- W2079262414 hasConcept C538909803 @default.
- W2079262414 hasConcept C544657597 @default.
- W2079262414 hasConcept C553756173 @default.
- W2079262414 hasConcept C55493867 @default.
- W2079262414 hasConcept C62231903 @default.
- W2079262414 hasConcept C86803240 @default.
- W2079262414 hasConceptScore W2079262414C150903083 @default.
- W2079262414 hasConceptScore W2079262414C165069038 @default.
- W2079262414 hasConceptScore W2079262414C178790620 @default.
- W2079262414 hasConceptScore W2079262414C181199279 @default.
- W2079262414 hasConceptScore W2079262414C185592680 @default.
- W2079262414 hasConceptScore W2079262414C207001950 @default.
- W2079262414 hasConceptScore W2079262414C2778760513 @default.
- W2079262414 hasConceptScore W2079262414C538909803 @default.
- W2079262414 hasConceptScore W2079262414C544657597 @default.
- W2079262414 hasConceptScore W2079262414C553756173 @default.
- W2079262414 hasConceptScore W2079262414C55493867 @default.
- W2079262414 hasConceptScore W2079262414C62231903 @default.
- W2079262414 hasConceptScore W2079262414C86803240 @default.
- W2079262414 hasLocation W20792624141 @default.
- W2079262414 hasLocation W20792624142 @default.
- W2079262414 hasLocation W20792624143 @default.
- W2079262414 hasLocation W20792624144 @default.
- W2079262414 hasOpenAccess W2079262414 @default.
- W2079262414 hasPrimaryLocation W20792624141 @default.
- W2079262414 hasRelatedWork W1965809819 @default.
- W2079262414 hasRelatedWork W1986965253 @default.
- W2079262414 hasRelatedWork W1997196963 @default.
- W2079262414 hasRelatedWork W2007353191 @default.
- W2079262414 hasRelatedWork W2038121409 @default.
- W2079262414 hasRelatedWork W2330363748 @default.
- W2079262414 hasRelatedWork W2461803461 @default.
- W2079262414 hasRelatedWork W3154365496 @default.
- W2079262414 hasRelatedWork W4200160080 @default.
- W2079262414 hasRelatedWork W790312177 @default.
- W2079262414 hasVolume "25" @default.
- W2079262414 isParatext "false" @default.
- W2079262414 isRetracted "false" @default.
- W2079262414 magId "2079262414" @default.
- W2079262414 workType "article" @default.