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- W2079275537 abstract "From each of two lentogenic Newcastle disease virus (NDV) strains of the type LaSota and Hitchner B1 a virulent subpopulation could be obtained. The two subpopulations were—in comparison to the two parent viruses—more resistant to the lipid solvent chloroform and more stable against thermal degradation. Also, the glycoproteins haemagglutinin and F (fusion) were more stable against thermal inactivation. Electron microscopic observations revealed in terms of size and morphology all of the characteristics of NDV. Both subpopulations possessed, however, the same elution kinetics as their respective parent strains. The intracerebral and intravenous pathogenicity indices as well as the mean death times of the two subpopulations allow to classify these viruses as virulent Newcastle disease viruses. Nous avons pu obtenir une sous-population virulente à partir de chacune des deux souches lentogènes du virus de la maladie de Newcastle (NDV): les souches LaSota et Hitchner B 1. Les deux sous-populations étaient—comparées avec les deux virus parents—plus résistantes au chloroforme et plus thermo-stables. De même, les glucoprotéines hémagglutinine et F (fusion) se sont révélées plus résistantes à l'inactivation par la chaleur. Les observations effectuées au microscope électronique ont permis d'identifier toutes les caractéristiques de taille et de morphologie du NDV. Les deux sous-populations possédaient cependant les mêmes cinétiques d'élution que leurs souches parentes respectives. Les indices de pathogénicité intra-cérébrale et intraveineuse ainsi que les délais létaux moyens des deux sous-populations nous permettent de classer ces deux virus comme des virus virulents de la maladie de Newcastle." @default.
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- W2079275537 date "1979-01-01" @default.
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- W2079275537 title "Isolation and biological properties of virulent subpopulations from lentogenic Newcastle disease virus strains" @default.
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- W2079275537 doi "https://doi.org/10.1016/0147-9571(79)90090-0" @default.
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