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- W2079280859 abstract "The effect of pH on the in vitro absorption of flufenamic acid is studied using the “everted sac” technique. The study reveals that the passage of this drug through the gut membrane is by passive diffusion. The amount diffusing through is dependent on the pH. Using Fick's diffusion law, a method is presented to calculate the apparent permeability constant at each pH value, and to determine the permeability constant. The relative surface area of the membrane through which diffusion of the drug takes place is estimated from the amount of “bound” drug." @default.
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- W2079280859 date "1966-12-01" @default.
- W2079280859 modified "2023-09-27" @default.
- W2079280859 title "Effect of pH on the In Vitro Absorption of Flufenamic Acid" @default.
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- W2079280859 doi "https://doi.org/10.1002/jps.2600551212" @default.
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