FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079281714> ?p ?o ?g. }

• W2079281714 endingPage "1395" @default.
• W2079281714 startingPage "1380" @default.
• W2079281714 abstract "Proteins in the PYR/PYL/RCAR family (PYLs) are known as receptors for the phytohormone ABA. Upon ABA binding, PYL adopts a conformation that allows it to interact with and inhibit clade A protein phosphatase 2Cs (PP2Cs), which are known as the co-receptors for ABA. Inhibition of the PP2Cs then leads to the activation of the SnRK2 family protein kinases that phosphorylate and activate downstream effectors in ABA response pathways. The PYL family has 14 members in Arabidopsis, 13 of which have been demonstrated to function as ABA receptors. The function of PYL13, a divergent member of the family, has been enigmatic. We report here that PYL13 differs from the other PYLs in three key residues that affect ABA perception, and mutations in these three residues can convert PYL13 into a partially functional ABA receptor. Transgenic plants overexpressing PYL13 show increased ABA sensitivity in seed germination and postgermination seedling establishment as well as decreased stomatal conductance, increased water-use efficiency, accelerated stress-responsive gene expression, and enhanced drought resistance. pyl13 mutant plants are less sensitive to ABA inhibition of postgermination seedling establishment. PYL13 interacts with and inhibits some members of clade A PP2Cs (PP2CA in particular) in an ABA-independent manner. PYL13 also interacts with the other PYLs and antagonizes their function as ABA receptors. Our results show that PYL13 is not an ABA receptor but can modulate the ABA pathway by interacting with and inhibiting both the PYL receptors and the PP2C co-receptors." @default.
• W2079281714 created "2016-06-24" @default.
• W2079281714 creator A5004149609 @default.
• W2079281714 creator A5005311855 @default.
• W2079281714 creator A5029410827 @default.
• W2079281714 creator A5031944606 @default.
• W2079281714 creator A5035168940 @default.
• W2079281714 creator A5038994209 @default.
• W2079281714 creator A5045441769 @default.
• W2079281714 creator A5049293054 @default.
• W2079281714 creator A5057823258 @default.
• W2079281714 date "2013-11-05" @default.
• W2079281714 modified "2023-10-10" @default.
• W2079281714 title "The unique mode of action of a divergent member of the ABA-receptor protein family in ABA and stress signaling" @default.
• W2079281714 cites W1785790772 @default.
• W2079281714 cites W1972028056 @default.
• W2079281714 cites W1974131529 @default.
• W2079281714 cites W1978838242 @default.
• W2079281714 cites W1997038372 @default.
• W2079281714 cites W1997530089 @default.
• W2079281714 cites W2010766544 @default.
• W2079281714 cites W2022682338 @default.
• W2079281714 cites W2026011395 @default.
• W2079281714 cites W2043124040 @default.
• W2079281714 cites W2044654183 @default.
• W2079281714 cites W2044809277 @default.
• W2079281714 cites W2045272783 @default.
• W2079281714 cites W2052062475 @default.
• W2079281714 cites W2052821301 @default.
• W2079281714 cites W2056385567 @default.
• W2079281714 cites W2060396596 @default.
• W2079281714 cites W2067026128 @default.
• W2079281714 cites W2078821795 @default.
• W2079281714 cites W2078929441 @default.
• W2079281714 cites W2083479533 @default.
• W2079281714 cites W2090936658 @default.
• W2079281714 cites W2093481978 @default.
• W2079281714 cites W2097224448 @default.
• W2079281714 cites W2099540066 @default.
• W2079281714 cites W2100596643 @default.
• W2079281714 cites W2102842520 @default.
• W2079281714 cites W2106396116 @default.
• W2079281714 cites W2107245457 @default.
• W2079281714 cites W2107277218 @default.
• W2079281714 cites W2109411650 @default.
• W2079281714 cites W2122828310 @default.
• W2079281714 cites W2123037553 @default.
• W2079281714 cites W2126963174 @default.
• W2079281714 cites W2127417807 @default.
• W2079281714 cites W2129074430 @default.
• W2079281714 cites W2134030532 @default.
• W2079281714 cites W2137015675 @default.
• W2079281714 cites W2138032440 @default.
• W2079281714 cites W2139316703 @default.
• W2079281714 cites W2144905863 @default.
• W2079281714 cites W2150783230 @default.
• W2079281714 cites W2155619616 @default.
• W2079281714 cites W2155968416 @default.
• W2079281714 cites W2156166308 @default.
• W2079281714 cites W2161591650 @default.
• W2079281714 cites W2163657147 @default.
• W2079281714 cites W2165584051 @default.
• W2079281714 cites W2165628747 @default.
• W2079281714 cites W2167784171 @default.
• W2079281714 doi "https://doi.org/10.1038/cr.2013.149" @default.
• W2079281714 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3847577" @default.
• W2079281714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24189045" @default.
• W2079281714 hasPublicationYear "2013" @default.
• W2079281714 type Work @default.
• W2079281714 sameAs 2079281714 @default.
• W2079281714 citedByCount "99" @default.
• W2079281714 countsByYear W20792817142014 @default.
• W2079281714 countsByYear W20792817142015 @default.
• W2079281714 countsByYear W20792817142016 @default.
• W2079281714 countsByYear W20792817142017 @default.
• W2079281714 countsByYear W20792817142018 @default.
• W2079281714 countsByYear W20792817142019 @default.
• W2079281714 countsByYear W20792817142020 @default.
• W2079281714 countsByYear W20792817142021 @default.
• W2079281714 countsByYear W20792817142022 @default.
• W2079281714 countsByYear W20792817142023 @default.
• W2079281714 crossrefType "journal-article" @default.
• W2079281714 hasAuthorship W2079281714A5004149609 @default.
• W2079281714 hasAuthorship W2079281714A5005311855 @default.
• W2079281714 hasAuthorship W2079281714A5029410827 @default.
• W2079281714 hasAuthorship W2079281714A5031944606 @default.
• W2079281714 hasAuthorship W2079281714A5035168940 @default.
• W2079281714 hasAuthorship W2079281714A5038994209 @default.
• W2079281714 hasAuthorship W2079281714A5045441769 @default.
• W2079281714 hasAuthorship W2079281714A5049293054 @default.
• W2079281714 hasAuthorship W2079281714A5057823258 @default.
• W2079281714 hasBestOaLocation W20792817141 @default.
• W2079281714 hasConcept C104317684 @default.
• W2079281714 hasConcept C11960822 @default.
• W2079281714 hasConcept C143065580 @default.
• W2079281714 hasConcept C150194340 @default.
• W2079281714 hasConcept C170493617 @default.
• W2079281714 hasConcept C178666793 @default.

• next