FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079287487> ?p ?o ?g. }

• W2079287487 endingPage "386" @default.
• W2079287487 startingPage "382" @default.
• W2079287487 abstract "Primary palmar hyperhidrosis is a condition marked by excessive perspiration and is reported to have an incidence of 1% in the Western population. It is a potentially disabling disorder that interferes with social, psychological, and professional activities. Over the past several years, several investigators have reported a positive family history in their patients treated for hyperhidrosis. To date, the cause is unknown; furthermore, epidemiologic data are scarce and inadequate.To characterize the genetic contribution to hyperhidrosis, we conducted a prospective study of 58 consecutive patients with palmar, plantar, or axillary hyperhidrosis treated with thoracoscopic sympathectomy from September 1993 to July 1999. Forty-nine of the 58 probands volunteered family history data for these analyses (84% response rate). A standardized questionnaire was administered during the postoperative visit or by phone interview, and a detailed family history was obtained. The same questionnaire was also administered to a set of 20 control patients. The familial aggregation of hyperhidrosis has been quantified by estimating the recurrence risks to the offspring, parents, siblings, aunts, uncles, and cousins of 49 probands and 20 controls. We estimated the penetrance by use of a genetic analysis program.Thirty-two of 49 (65%) reported a positive family history in our hyperhidrosis group, and 0% reported a positive family history in our control group. A recurrence risk of 0.28 in the offspring of probands compared with frequency of 0.01 in the general population provides strong evidence for vertical transmission of this disorder in pedigrees and is further supported by the 0.14 risk to the parents of the probands. The results indicate that the disease allele is present in about 5% of the population and that one or two copies of the allele will result in hyperhidrosis 25% of the time, whereas the normal allele will result in hyperhidrosis less than 1% of the time.We conclude that primary palmar hyperhidrosis is a hereditary disorder, with variable penetrance and no proof of sex-linked transmission. However, this does not exclude other possible causes, and we anticipate that genetic confirmation of this disorder may lead to earlier diagnoses and advances in medical and psychosocial interventions." @default.
• W2079287487 created "2016-06-24" @default.
• W2079287487 creator A5021466131 @default.
• W2079287487 creator A5027394953 @default.
• W2079287487 creator A5035750579 @default.
• W2079287487 creator A5070269135 @default.
• W2079287487 date "2002-02-01" @default.
• W2079287487 modified "2023-10-18" @default.
• W2079287487 title "Palmar hyperhidrosis: Evidence of genetic transmission" @default.
• W2079287487 cites W1765369324 @default.
• W2079287487 cites W1963922438 @default.
• W2079287487 cites W1981669963 @default.
• W2079287487 cites W1982019854 @default.
• W2079287487 cites W1984785660 @default.
• W2079287487 cites W1988002698 @default.
• W2079287487 cites W1992354174 @default.
• W2079287487 cites W1995993856 @default.
• W2079287487 cites W1998698948 @default.
• W2079287487 cites W2003898795 @default.
• W2079287487 cites W2009840299 @default.
• W2079287487 cites W2011835490 @default.
• W2079287487 cites W2019945839 @default.
• W2079287487 cites W2023404273 @default.
• W2079287487 cites W2025908546 @default.
• W2079287487 cites W2029929101 @default.
• W2079287487 cites W2031136760 @default.
• W2079287487 cites W2043065933 @default.
• W2079287487 cites W2048741547 @default.
• W2079287487 cites W2048810492 @default.
• W2079287487 cites W2053855180 @default.
• W2079287487 cites W2064387317 @default.
• W2079287487 cites W2080304763 @default.
• W2079287487 cites W2082429525 @default.
• W2079287487 cites W2086224987 @default.
• W2079287487 cites W2104578391 @default.
• W2079287487 cites W2118075097 @default.
• W2079287487 cites W2170598085 @default.
• W2079287487 cites W2331616223 @default.
• W2079287487 cites W3142229154 @default.
• W2079287487 cites W4255513037 @default.
• W2079287487 doi "https://doi.org/10.1067/mva.2002.119507" @default.
• W2079287487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11854739" @default.
• W2079287487 hasPublicationYear "2002" @default.
• W2079287487 type Work @default.
• W2079287487 sameAs 2079287487 @default.
• W2079287487 citedByCount "186" @default.
• W2079287487 countsByYear W20792874872012 @default.
• W2079287487 countsByYear W20792874872013 @default.
• W2079287487 countsByYear W20792874872014 @default.
• W2079287487 countsByYear W20792874872015 @default.
• W2079287487 countsByYear W20792874872016 @default.
• W2079287487 countsByYear W20792874872017 @default.
• W2079287487 countsByYear W20792874872018 @default.
• W2079287487 countsByYear W20792874872019 @default.
• W2079287487 countsByYear W20792874872020 @default.
• W2079287487 countsByYear W20792874872021 @default.
• W2079287487 countsByYear W20792874872022 @default.
• W2079287487 countsByYear W20792874872023 @default.
• W2079287487 crossrefType "journal-article" @default.
• W2079287487 hasAuthorship W2079287487A5021466131 @default.
• W2079287487 hasAuthorship W2079287487A5027394953 @default.
• W2079287487 hasAuthorship W2079287487A5035750579 @default.
• W2079287487 hasAuthorship W2079287487A5070269135 @default.
• W2079287487 hasBestOaLocation W20792874871 @default.
• W2079287487 hasConcept C104317684 @default.
• W2079287487 hasConcept C112672928 @default.
• W2079287487 hasConcept C127716648 @default.
• W2079287487 hasConcept C141071460 @default.
• W2079287487 hasConcept C185592680 @default.
• W2079287487 hasConcept C1862650 @default.
• W2079287487 hasConcept C187212893 @default.
• W2079287487 hasConcept C188997412 @default.
• W2079287487 hasConcept C200544954 @default.
• W2079287487 hasConcept C2778650131 @default.
• W2079287487 hasConcept C2779234561 @default.
• W2079287487 hasConcept C2781179581 @default.
• W2079287487 hasConcept C2908647359 @default.
• W2079287487 hasConcept C501734568 @default.
• W2079287487 hasConcept C54355233 @default.
• W2079287487 hasConcept C55493867 @default.
• W2079287487 hasConcept C71924100 @default.
• W2079287487 hasConcept C86803240 @default.
• W2079287487 hasConcept C99454951 @default.
• W2079287487 hasConceptScore W2079287487C104317684 @default.
• W2079287487 hasConceptScore W2079287487C112672928 @default.
• W2079287487 hasConceptScore W2079287487C127716648 @default.
• W2079287487 hasConceptScore W2079287487C141071460 @default.
• W2079287487 hasConceptScore W2079287487C185592680 @default.
• W2079287487 hasConceptScore W2079287487C1862650 @default.
• W2079287487 hasConceptScore W2079287487C187212893 @default.
• W2079287487 hasConceptScore W2079287487C188997412 @default.
• W2079287487 hasConceptScore W2079287487C200544954 @default.
• W2079287487 hasConceptScore W2079287487C2778650131 @default.
• W2079287487 hasConceptScore W2079287487C2779234561 @default.
• W2079287487 hasConceptScore W2079287487C2781179581 @default.
• W2079287487 hasConceptScore W2079287487C2908647359 @default.
• W2079287487 hasConceptScore W2079287487C501734568 @default.
• W2079287487 hasConceptScore W2079287487C54355233 @default.

• next