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• W2079292457 startingPage "617" @default.
• W2079292457 abstract "The respiratory region of the nasal mucosa is innervated by the ethmoidal nerve. Chemical nociceptive stimulation of this area leads to upper airway reflexes that prevent access of noxious substances to the respiratory tract and the lungs. In the present study we examined the localization of the cell bodies of the respective primary afferent fibres within the trigeminal ganglion, as well as their central projections. In 25 rats a horseradish peroxidase-wheat germ agglutinin gel was applied to the right nasal cavity. The animals were killed after 48-72 h. For visualization of the tracer the tissue was processed according to the tetramethylbenzidine method. In the trigeminal ganglion almost all labelled cell bodies were localized in a medial band immediately caudal to the entrance of the ophthalmomaxillary branch. Transganglionic projections to the trigeminal brainstem nuclear complex were only localized in the superficial laminae of the subnucleus caudalis and in the subnucleus interpolaris, areas known to be involved in processing of nociceptive information. An additional labelled terminal field was observed in the interstitial subnucleus of the nucleus tractus solitarius, which is involved in respiratory control. These results are in favour of the hypothesis that the ethmoidal nerve in rat constitutes the afferent limb of protective upper airway reflexes since it transmits mainly nociceptive information." @default.
• W2079292457 created "2016-06-24" @default.
• W2079292457 creator A5007800426 @default.
• W2079292457 creator A5049770785 @default.
• W2079292457 date "1991-01-01" @default.
• W2079292457 modified "2023-09-30" @default.
• W2079292457 title "Central projections of trigeminal primary afferents innervating the nasal mucosa: A horseradish peroxidase study in the rat" @default.
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• W2079292457 doi "https://doi.org/10.1016/0306-4522(91)90354-q" @default.
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