FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079323180> ?p ?o ?g. }

• W2079323180 endingPage "271" @default.
• W2079323180 startingPage "265" @default.
• W2079323180 abstract "To investigate paraventricular hypothalamic neuronal actions responsible for the effects of neurotransmitters on feeding, and to test the notion that a single population of cells there could account for feeding effects, hypothalamic slices containing the paraventricular nucleus (PVN) were prepared from rats. Electrophysiological responses of individual PVN neurons to feeding-inducing agents norepinephrine (NE) and gamma-aminobutyric acid (GABA), and to anorexic agents serotonin (5-HT) and histamine (Hist) were examined. NE inhibited neuronal activity through alpha 2-adrenergic receptors, and excited through alpha 1-receptors. alpha 2-receptors are known to mediate the behavioral effect of NE. NE inhibited most clearly those neurons that otherwise fired continuously in this type of in vitro preparation. GABA affected the activity of 37% of the neurons tested, primarily by inhibition. The inhibitory action of GABA can be related to its feeding-inducing effect. GABA in PVN can also attenuate excitatory responses and enhance inhibitory responses to NE or 5-HT. 5-HT caused excitatory and inhibitory responses with the former action outnumbering the latter by approximately 3 to 1. Since this would result in a net excitation, it appears that 5-HT in PVN inhibits feeding mainly by exciting neuronal activity. Hist excited 72% and inhibited only 2% of PVN neurons. The excitation was blocked by H1-antagonists, which have been shown to mediate Hist effect on feeding. Comparing across neurons, the inhibitory response to NE was correlated with that to GABA, but not with any responses to 5-HT or Hist. The excitatory responses to Hist correlated with 5-HT responses.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2079323180 created "2016-06-24" @default.
• W2079323180 creator A5076296606 @default.
• W2079323180 creator A5086866710 @default.
• W2079323180 date "1989-08-01" @default.
• W2079323180 modified "2023-09-26" @default.
• W2079323180 title "Responses of hypothalamic paraventricular neurons in vitro to norepinephrine and other feeding-relevant agents" @default.
• W2079323180 cites W1967521171 @default.
• W2079323180 cites W1969265436 @default.
• W2079323180 cites W1969272581 @default.
• W2079323180 cites W1969985618 @default.
• W2079323180 cites W1976801672 @default.
• W2079323180 cites W1980067334 @default.
• W2079323180 cites W1986847341 @default.
• W2079323180 cites W1986879794 @default.
• W2079323180 cites W1996405310 @default.
• W2079323180 cites W2001769763 @default.
• W2079323180 cites W2006923825 @default.
• W2079323180 cites W2008544154 @default.
• W2079323180 cites W2009308275 @default.
• W2079323180 cites W2009928105 @default.
• W2079323180 cites W2010285200 @default.
• W2079323180 cites W2015681027 @default.
• W2079323180 cites W2020719309 @default.
• W2079323180 cites W2025830876 @default.
• W2079323180 cites W2031329138 @default.
• W2079323180 cites W2035541519 @default.
• W2079323180 cites W2046505969 @default.
• W2079323180 cites W2047009822 @default.
• W2079323180 cites W2055753190 @default.
• W2079323180 cites W2069721792 @default.
• W2079323180 cites W2069851163 @default.
• W2079323180 cites W2070993638 @default.
• W2079323180 cites W2071101349 @default.
• W2079323180 cites W2071273152 @default.
• W2079323180 doi "https://doi.org/10.1016/0031-9384(89)90266-7" @default.
• W2079323180 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2574890" @default.
• W2079323180 hasPublicationYear "1989" @default.
• W2079323180 type Work @default.
• W2079323180 sameAs 2079323180 @default.
• W2079323180 citedByCount "60" @default.
• W2079323180 countsByYear W20793231802012 @default.
• W2079323180 countsByYear W20793231802013 @default.
• W2079323180 countsByYear W20793231802016 @default.
• W2079323180 crossrefType "journal-article" @default.
• W2079323180 hasAuthorship W2079323180A5076296606 @default.
• W2079323180 hasAuthorship W2079323180A5086866710 @default.
• W2079323180 hasConcept C112592302 @default.
• W2079323180 hasConcept C126322002 @default.
• W2079323180 hasConcept C134018914 @default.
• W2079323180 hasConcept C169760540 @default.
• W2079323180 hasConcept C170493617 @default.
• W2079323180 hasConcept C17077164 @default.
• W2079323180 hasConcept C185263204 @default.
• W2079323180 hasConcept C185592680 @default.
• W2079323180 hasConcept C2775864247 @default.
• W2079323180 hasConcept C2777003273 @default.
• W2079323180 hasConcept C2778514916 @default.
• W2079323180 hasConcept C2908647359 @default.
• W2079323180 hasConcept C513476851 @default.
• W2079323180 hasConcept C71924100 @default.
• W2079323180 hasConcept C86803240 @default.
• W2079323180 hasConcept C99454951 @default.
• W2079323180 hasConceptScore W2079323180C112592302 @default.
• W2079323180 hasConceptScore W2079323180C126322002 @default.
• W2079323180 hasConceptScore W2079323180C134018914 @default.
• W2079323180 hasConceptScore W2079323180C169760540 @default.
• W2079323180 hasConceptScore W2079323180C170493617 @default.
• W2079323180 hasConceptScore W2079323180C17077164 @default.
• W2079323180 hasConceptScore W2079323180C185263204 @default.
• W2079323180 hasConceptScore W2079323180C185592680 @default.
• W2079323180 hasConceptScore W2079323180C2775864247 @default.
• W2079323180 hasConceptScore W2079323180C2777003273 @default.
• W2079323180 hasConceptScore W2079323180C2778514916 @default.
• W2079323180 hasConceptScore W2079323180C2908647359 @default.
• W2079323180 hasConceptScore W2079323180C513476851 @default.
• W2079323180 hasConceptScore W2079323180C71924100 @default.
• W2079323180 hasConceptScore W2079323180C86803240 @default.
• W2079323180 hasConceptScore W2079323180C99454951 @default.
• W2079323180 hasIssue "2" @default.
• W2079323180 hasLocation W20793231801 @default.
• W2079323180 hasLocation W20793231802 @default.
• W2079323180 hasOpenAccess W2079323180 @default.
• W2079323180 hasPrimaryLocation W20793231801 @default.
• W2079323180 hasRelatedWork W1971453675 @default.
• W2079323180 hasRelatedWork W1984541950 @default.
• W2079323180 hasRelatedWork W2006923825 @default.
• W2079323180 hasRelatedWork W2007920416 @default.
• W2079323180 hasRelatedWork W2029739536 @default.
• W2079323180 hasRelatedWork W2034583712 @default.
• W2079323180 hasRelatedWork W2053203668 @default.
• W2079323180 hasRelatedWork W2062579683 @default.
• W2079323180 hasRelatedWork W2166688422 @default.
• W2079323180 hasRelatedWork W2414846389 @default.
• W2079323180 hasVolume "46" @default.
• W2079323180 isParatext "false" @default.
• W2079323180 isRetracted "false" @default.
• W2079323180 magId "2079323180" @default.

• next