Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079331899> ?p ?o ?g. }
- W2079331899 endingPage "119" @default.
- W2079331899 startingPage "114" @default.
- W2079331899 abstract "Objectives In chronic kidney disease (CKD), high FGF23 concentrations are associated with left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of FGF23 with left ventricular mass (LVM) and LVH in the general population and the influence of CKD remains uncertain. Methods C-terminal plasma FGF23 concentrations were measured, and LVM and LVH evaluated by echocardiogram among 2255 individuals ≥65 years in the Cardiovascular Health Study. Linear regression analysis adjusting for demographics, cardiovascular, and kidney related risk factors examined the associations of FGF23 concentrations with LVM. Analyses were stratified by CKD status and adjusted linear and logistic regression analysis explored the associations of FGF23 with LVM and LVH. Results Among the entire cohort, higher FGF23 concentrations were associated with greater LVM in adjusted analyses (β = 6.71 [95% CI 4.35–9.01] g per doubling of FGF23). 32% (n = 624) had CKD (eGFR <60 mL/min/1.73 m2 and/or urine albumin-to-creatinine ratio >30 mg/g). Associations were stronger among participants with CKD (p interaction = 0.006): LVM β = 9.71 [95% CI 5.86–13.56] g per doubling of FGF23 compared to those without CKD (β = 3.44 [95% CI 0.77, 6.11] g per doubling of FGF23). While there was no significant interaction between FGF23 and CKD for LVH (p interaction = 0.25), the OR (1.46 95% CI [1.20–1.77]) in the CKD group was statistically significant and of larger magnitude than the OR for in the no CKD group (1.12 [95% CI 0.97–1.48]). Conclusion In a large cohort of older community-dwelling adults, higher FGF23 concentrations were associated with greater LVM and LVH with stronger relationships in participants with CKD." @default.
- W2079331899 created "2016-06-24" @default.
- W2079331899 creator A5017572190 @default.
- W2079331899 creator A5022346670 @default.
- W2079331899 creator A5024425228 @default.
- W2079331899 creator A5030882947 @default.
- W2079331899 creator A5030943960 @default.
- W2079331899 creator A5032870005 @default.
- W2079331899 creator A5041104244 @default.
- W2079331899 creator A5049758084 @default.
- W2079331899 creator A5057364839 @default.
- W2079331899 creator A5064713352 @default.
- W2079331899 creator A5071585977 @default.
- W2079331899 creator A5076361487 @default.
- W2079331899 date "2013-11-01" @default.
- W2079331899 modified "2023-10-15" @default.
- W2079331899 title "Fibroblast growth factor 23, left ventricular mass, and left ventricular hypertrophy in community-dwelling older adults" @default.
- W2079331899 cites W1511208491 @default.
- W2079331899 cites W1803609188 @default.
- W2079331899 cites W1981403669 @default.
- W2079331899 cites W2003056396 @default.
- W2079331899 cites W2006102984 @default.
- W2079331899 cites W2015668150 @default.
- W2079331899 cites W2028094031 @default.
- W2079331899 cites W2032556546 @default.
- W2079331899 cites W2038393248 @default.
- W2079331899 cites W2042293234 @default.
- W2079331899 cites W2049382000 @default.
- W2079331899 cites W2058721308 @default.
- W2079331899 cites W2060108666 @default.
- W2079331899 cites W2063058274 @default.
- W2079331899 cites W2063069042 @default.
- W2079331899 cites W2078730571 @default.
- W2079331899 cites W2091948921 @default.
- W2079331899 cites W2094262605 @default.
- W2079331899 cites W2095948376 @default.
- W2079331899 cites W2107420262 @default.
- W2079331899 cites W2111097992 @default.
- W2079331899 cites W2111614075 @default.
- W2079331899 cites W2125079553 @default.
- W2079331899 cites W2125383113 @default.
- W2079331899 cites W2131843552 @default.
- W2079331899 cites W2135910107 @default.
- W2079331899 cites W2140575711 @default.
- W2079331899 cites W2157448600 @default.
- W2079331899 cites W2161197885 @default.
- W2079331899 cites W2162505180 @default.
- W2079331899 cites W2291483902 @default.
- W2079331899 cites W27593660 @default.
- W2079331899 doi "https://doi.org/10.1016/j.atherosclerosis.2013.09.002" @default.
- W2079331899 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3840534" @default.
- W2079331899 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24125420" @default.
- W2079331899 hasPublicationYear "2013" @default.
- W2079331899 type Work @default.
- W2079331899 sameAs 2079331899 @default.
- W2079331899 citedByCount "69" @default.
- W2079331899 countsByYear W20793318992014 @default.
- W2079331899 countsByYear W20793318992015 @default.
- W2079331899 countsByYear W20793318992016 @default.
- W2079331899 countsByYear W20793318992017 @default.
- W2079331899 countsByYear W20793318992018 @default.
- W2079331899 countsByYear W20793318992019 @default.
- W2079331899 countsByYear W20793318992020 @default.
- W2079331899 countsByYear W20793318992021 @default.
- W2079331899 countsByYear W20793318992022 @default.
- W2079331899 countsByYear W20793318992023 @default.
- W2079331899 crossrefType "journal-article" @default.
- W2079331899 hasAuthorship W2079331899A5017572190 @default.
- W2079331899 hasAuthorship W2079331899A5022346670 @default.
- W2079331899 hasAuthorship W2079331899A5024425228 @default.
- W2079331899 hasAuthorship W2079331899A5030882947 @default.
- W2079331899 hasAuthorship W2079331899A5030943960 @default.
- W2079331899 hasAuthorship W2079331899A5032870005 @default.
- W2079331899 hasAuthorship W2079331899A5041104244 @default.
- W2079331899 hasAuthorship W2079331899A5049758084 @default.
- W2079331899 hasAuthorship W2079331899A5057364839 @default.
- W2079331899 hasAuthorship W2079331899A5064713352 @default.
- W2079331899 hasAuthorship W2079331899A5071585977 @default.
- W2079331899 hasAuthorship W2079331899A5076361487 @default.
- W2079331899 hasBestOaLocation W20793318992 @default.
- W2079331899 hasConcept C114276007 @default.
- W2079331899 hasConcept C126322002 @default.
- W2079331899 hasConcept C134018914 @default.
- W2079331899 hasConcept C164705383 @default.
- W2079331899 hasConcept C2776002628 @default.
- W2079331899 hasConcept C2776174234 @default.
- W2079331899 hasConcept C2778653478 @default.
- W2079331899 hasConcept C2780306776 @default.
- W2079331899 hasConcept C2781208988 @default.
- W2079331899 hasConcept C2908647359 @default.
- W2079331899 hasConcept C519063684 @default.
- W2079331899 hasConcept C71924100 @default.
- W2079331899 hasConcept C72563966 @default.
- W2079331899 hasConcept C84393581 @default.
- W2079331899 hasConcept C99454951 @default.
- W2079331899 hasConceptScore W2079331899C114276007 @default.
- W2079331899 hasConceptScore W2079331899C126322002 @default.
- W2079331899 hasConceptScore W2079331899C134018914 @default.