Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079338730> ?p ?o ?g. }
- W2079338730 endingPage "92" @default.
- W2079338730 startingPage "73" @default.
- W2079338730 abstract "To outline how hypoxia profoundly affects neuronal functionality and thus compromise exercise-performance.Investigations using electroencephalography (EEG) and transcranial magnetic stimulation (TMS) detecting neuronal changes at rest and those studying fatiguing effects on whole-body exercise performance in acute (AH) and chronic hypoxia (CH) were evaluated.At rest during very early hypoxia (<1-h), slowing of cerebral neuronal activity is evident despite no change in corticospinal excitability. As time in hypoxia progresses (3-h), increased corticospinal excitability becomes evident; however, changes in neuronal activity are unknown. Prolonged exposure (3-5 d) causes a respiratory alkalosis which modulates Na+ channels, potentially explaining reduced neuronal excitability. Locomotor exercise in AH exacerbates the development of peripheral-fatigue; as the severity of hypoxia increases, mechanisms of peripheral-fatigue become less dominant and CNS hypoxia becomes the predominant factor. The greatest central-fatigue in AH occurs when SaO2 is ≤75%, a level that coincides with increasing impairments in neuronal activity. CH does not improve the level of peripheral-fatigue observed in AH; however, it attenuates the development of central-fatigue paralleling increases in cerebral O2 availability and corticospinal excitability.The attenuated development of central-fatigue in CH might explain, the improvements in locomotor exercise-performance commonly observed after acclimatisation to high altitude." @default.
- W2079338730 created "2016-06-24" @default.
- W2079338730 creator A5011184004 @default.
- W2079338730 creator A5016633269 @default.
- W2079338730 creator A5060438113 @default.
- W2079338730 date "2014-04-03" @default.
- W2079338730 modified "2023-10-06" @default.
- W2079338730 title "Acute and chronic hypoxia: implications for cerebral function and exercise tolerance" @default.
- W2079338730 cites W113471440 @default.
- W2079338730 cites W1206391664 @default.
- W2079338730 cites W13841979 @default.
- W2079338730 cites W1494341793 @default.
- W2079338730 cites W1500634225 @default.
- W2079338730 cites W1546019921 @default.
- W2079338730 cites W1563015028 @default.
- W2079338730 cites W1563306114 @default.
- W2079338730 cites W1577385726 @default.
- W2079338730 cites W1598293267 @default.
- W2079338730 cites W1737007099 @default.
- W2079338730 cites W1914048043 @default.
- W2079338730 cites W1947378103 @default.
- W2079338730 cites W1965149513 @default.
- W2079338730 cites W1971990609 @default.
- W2079338730 cites W1975080955 @default.
- W2079338730 cites W1975931899 @default.
- W2079338730 cites W1983278061 @default.
- W2079338730 cites W199190945 @default.
- W2079338730 cites W2005547317 @default.
- W2079338730 cites W2006681786 @default.
- W2079338730 cites W2006815061 @default.
- W2079338730 cites W2008214949 @default.
- W2079338730 cites W2014254261 @default.
- W2079338730 cites W2016133211 @default.
- W2079338730 cites W2020806485 @default.
- W2079338730 cites W2021833123 @default.
- W2079338730 cites W2024644842 @default.
- W2079338730 cites W2024906708 @default.
- W2079338730 cites W202502296 @default.
- W2079338730 cites W2026590792 @default.
- W2079338730 cites W2032785172 @default.
- W2079338730 cites W2034651386 @default.
- W2079338730 cites W2035540062 @default.
- W2079338730 cites W2038170042 @default.
- W2079338730 cites W2044192936 @default.
- W2079338730 cites W2047684905 @default.
- W2079338730 cites W2052471278 @default.
- W2079338730 cites W2053442477 @default.
- W2079338730 cites W2054117980 @default.
- W2079338730 cites W2054446785 @default.
- W2079338730 cites W2055664991 @default.
- W2079338730 cites W2060932201 @default.
- W2079338730 cites W2061251161 @default.
- W2079338730 cites W2062933306 @default.
- W2079338730 cites W2064751005 @default.
- W2079338730 cites W2065376665 @default.
- W2079338730 cites W2074140397 @default.
- W2079338730 cites W2079564307 @default.
- W2079338730 cites W2080776366 @default.
- W2079338730 cites W2085452613 @default.
- W2079338730 cites W2086952037 @default.
- W2079338730 cites W2087065389 @default.
- W2079338730 cites W2087580407 @default.
- W2079338730 cites W2089121929 @default.
- W2079338730 cites W2089341050 @default.
- W2079338730 cites W2092283978 @default.
- W2079338730 cites W2092913529 @default.
- W2079338730 cites W2093415761 @default.
- W2079338730 cites W2098787652 @default.
- W2079338730 cites W2099628475 @default.
- W2079338730 cites W2099807559 @default.
- W2079338730 cites W2102294783 @default.
- W2079338730 cites W2102570073 @default.
- W2079338730 cites W2103463152 @default.
- W2079338730 cites W2103716936 @default.
- W2079338730 cites W2104336384 @default.
- W2079338730 cites W2105370141 @default.
- W2079338730 cites W2107775225 @default.
- W2079338730 cites W2108354433 @default.
- W2079338730 cites W2110661779 @default.
- W2079338730 cites W2115398282 @default.
- W2079338730 cites W2116404606 @default.
- W2079338730 cites W2116778599 @default.
- W2079338730 cites W2124261451 @default.
- W2079338730 cites W2125929079 @default.
- W2079338730 cites W2128180936 @default.
- W2079338730 cites W2129430141 @default.
- W2079338730 cites W2131453549 @default.
- W2079338730 cites W2133244276 @default.
- W2079338730 cites W2134494243 @default.
- W2079338730 cites W2135100321 @default.
- W2079338730 cites W2135576626 @default.
- W2079338730 cites W2137148755 @default.
- W2079338730 cites W2138070678 @default.
- W2079338730 cites W2138817745 @default.
- W2079338730 cites W2141522309 @default.
- W2079338730 cites W2142379914 @default.
- W2079338730 cites W2146329825 @default.
- W2079338730 cites W2148943667 @default.