FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079341791> ?p ?o ?g. }

• W2079341791 endingPage "13" @default.
• W2079341791 startingPage "6" @default.
• W2079341791 abstract "The 75% ethanol extract from guava (Psidium guajava Linn.) leaves was extracted further, in turn, with CH2Cl2, EtOAc and n-BuOH to afford four fractions, CH2Cl2-soluble, EtOAc-soluble, n-BuOH-soluble and residual extract fractions. Both the n-BuOH-soluble and EtOAc-soluble fractions showed high inhibitory activity against α-glucosidase and α-amylase. Seven pure flavonoid compounds, quercetin (1), kaempferol (2), guaijaverin (3), avicularin (4), myricetin (5), hyperin (6) and apigenin (7), were isolated (using enzyme assay-guide fractionation method) from the n-BuOH-soluble and EtOAc-soluble fractions. The structures of these pure compounds were determined on the basis of MS and NMR data and the activities of these compounds were evaluated. Compounds 1, 2 and 5 showed high inhibitory activities, with IC50 values of 3.5 mM, 5.2 mM and 3.0 mM against sucrase, with IC50 values of 4.8 mM, 5.6 mM and 4.1 mM against maltase and with IC50 values of 4.8 mM, 5.3 mM and 4.3 mM against α-amylase, respectively. We found that myricetin showed the most powerful activity among these compounds with a 70% inhibition against sucrase at a concentration of 1.5 mg/ml. The hydroxyl group at the 3-position on the A-ring and a number of hydroxyl groups attached to the C-ring played important roles in the inhibition activity. There was an obvious synergistic effect (the mixing action of two compounds) against α-glucosidase, but against α-amylase this was not found. This is the first study of the active compositions of guava leaves and the biological activity of the active compositions against α-glucosidase and α-amylase." @default.
• W2079341791 created "2016-06-24" @default.
• W2079341791 creator A5015737692 @default.
• W2079341791 creator A5029381220 @default.
• W2079341791 creator A5062902661 @default.
• W2079341791 date "2010-11-01" @default.
• W2079341791 modified "2023-10-01" @default.
• W2079341791 title "α-Glucosidase and α-amylase inhibitory activities of guava leaves" @default.
• W2079341791 cites W1718201877 @default.
• W2079341791 cites W1983404020 @default.
• W2079341791 cites W1992757969 @default.
• W2079341791 cites W1993382405 @default.
• W2079341791 cites W1996784849 @default.
• W2079341791 cites W1997786669 @default.
• W2079341791 cites W2011253184 @default.
• W2079341791 cites W2011592968 @default.
• W2079341791 cites W2014177638 @default.
• W2079341791 cites W2022778645 @default.
• W2079341791 cites W2026049307 @default.
• W2079341791 cites W2027894015 @default.
• W2079341791 cites W2032954913 @default.
• W2079341791 cites W2043969520 @default.
• W2079341791 cites W2056459369 @default.
• W2079341791 cites W2063050880 @default.
• W2079341791 cites W2075033480 @default.
• W2079341791 cites W2089019238 @default.
• W2079341791 cites W2094269209 @default.
• W2079341791 cites W2104478003 @default.
• W2079341791 doi "https://doi.org/10.1016/j.foodchem.2010.03.088" @default.
• W2079341791 hasPublicationYear "2010" @default.
• W2079341791 type Work @default.
• W2079341791 sameAs 2079341791 @default.
• W2079341791 citedByCount "257" @default.
• W2079341791 countsByYear W20793417912012 @default.
• W2079341791 countsByYear W20793417912013 @default.
• W2079341791 countsByYear W20793417912014 @default.
• W2079341791 countsByYear W20793417912015 @default.
• W2079341791 countsByYear W20793417912016 @default.
• W2079341791 countsByYear W20793417912017 @default.
• W2079341791 countsByYear W20793417912018 @default.
• W2079341791 countsByYear W20793417912019 @default.
• W2079341791 countsByYear W20793417912020 @default.
• W2079341791 countsByYear W20793417912021 @default.
• W2079341791 countsByYear W20793417912022 @default.
• W2079341791 countsByYear W20793417912023 @default.
• W2079341791 crossrefType "journal-article" @default.
• W2079341791 hasAuthorship W2079341791A5015737692 @default.
• W2079341791 hasAuthorship W2079341791A5029381220 @default.
• W2079341791 hasAuthorship W2079341791A5062902661 @default.
• W2079341791 hasConcept C170835558 @default.
• W2079341791 hasConcept C181199279 @default.
• W2079341791 hasConcept C185592680 @default.
• W2079341791 hasConcept C202751555 @default.
• W2079341791 hasConcept C2776039999 @default.
• W2079341791 hasConcept C2777752497 @default.
• W2079341791 hasConcept C2777810353 @default.
• W2079341791 hasConcept C2778004101 @default.
• W2079341791 hasConcept C2778173338 @default.
• W2079341791 hasConcept C2778609962 @default.
• W2079341791 hasConcept C2778649499 @default.
• W2079341791 hasConcept C2779054382 @default.
• W2079341791 hasConcept C2781263971 @default.
• W2079341791 hasConcept C43617362 @default.
• W2079341791 hasConcept C55493867 @default.
• W2079341791 hasConcept C97428945 @default.
• W2079341791 hasConceptScore W2079341791C170835558 @default.
• W2079341791 hasConceptScore W2079341791C181199279 @default.
• W2079341791 hasConceptScore W2079341791C185592680 @default.
• W2079341791 hasConceptScore W2079341791C202751555 @default.
• W2079341791 hasConceptScore W2079341791C2776039999 @default.
• W2079341791 hasConceptScore W2079341791C2777752497 @default.
• W2079341791 hasConceptScore W2079341791C2777810353 @default.
• W2079341791 hasConceptScore W2079341791C2778004101 @default.
• W2079341791 hasConceptScore W2079341791C2778173338 @default.
• W2079341791 hasConceptScore W2079341791C2778609962 @default.
• W2079341791 hasConceptScore W2079341791C2778649499 @default.
• W2079341791 hasConceptScore W2079341791C2779054382 @default.
• W2079341791 hasConceptScore W2079341791C2781263971 @default.
• W2079341791 hasConceptScore W2079341791C43617362 @default.
• W2079341791 hasConceptScore W2079341791C55493867 @default.
• W2079341791 hasConceptScore W2079341791C97428945 @default.
• W2079341791 hasIssue "1" @default.
• W2079341791 hasLocation W20793417911 @default.
• W2079341791 hasOpenAccess W2079341791 @default.
• W2079341791 hasPrimaryLocation W20793417911 @default.
• W2079341791 hasRelatedWork W1967940610 @default.
• W2079341791 hasRelatedWork W2079341791 @default.
• W2079341791 hasRelatedWork W2182935648 @default.
• W2079341791 hasRelatedWork W2299980107 @default.
• W2079341791 hasRelatedWork W2349436834 @default.
• W2079341791 hasRelatedWork W2380853125 @default.
• W2079341791 hasRelatedWork W2383832551 @default.
• W2079341791 hasRelatedWork W3132231250 @default.
• W2079341791 hasRelatedWork W748692431 @default.
• W2079341791 hasRelatedWork W2487797362 @default.
• W2079341791 hasVolume "123" @default.
• W2079341791 isParatext "false" @default.
• W2079341791 isRetracted "false" @default.

• next