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• W207934189 abstract "The relation of depression to immunological assays is complex and variable. However, meta-analyses have demonstrated that depressed subjects are likely to show changes in several immune assays. Depressed subjects are likely to have changes in major immune cell classes with an increase in total white blood cell counts and a relative increase in numbers of neutrophils. However, the relative number of lymphocytes is likely to be reduced in depressed subjects. Depression also appears to be associated with increases in at least one measure of immune activation, although further investigations are clearly needed to replicate these interesting observations. Finally, depression is reliably associated with a suppression of mitogen-induced lymphocyte proliferation and with a reduction of NK activity. Despite the heterogeneity of findings, the effect sizes in the relationship between depression and lymphocyte proliferation and NK activity are large as compared to those observed in other areas of psychological and medical research. Several moderating factors may explain and account for the heterogeneity that has been found in the depression-immune results. Future immunologic studies in depressed subjects are needed to clarify the effects of gender and reproductive hormones on the relation between depression and immunity. Severity of melancholic symptoms and sleep disturbance appear to moderate the immune changes in depression but the biological mechanisms that account for the link between these neurovegetative symptoms and depression are not yet known. Finally, assessment of co-morbidity in depressed subjects deserves an increased focus. Data generated from our laboratory clearly show that assessment of alcohol- and tobacco dependence is critical in the interpretation of immune changes in depressed subjects. The clinical significance of changes in immune responses in depressed subjects remains an unanswered question. Studies that use immune measures with disease specific endpoints, as has been recently conducted in the study of VZV immune responses, would help identify the possible link between depression, immune system alterations, and health outcomes." @default.
• W207934189 created "2016-06-24" @default.
• W207934189 creator A5005936736 @default.
• W207934189 date "1999-01-01" @default.
• W207934189 modified "2023-10-16" @default.
• W207934189 title "Immune Correlates of Depression" @default.
• W207934189 cites W1511475277 @default.
• W207934189 cites W1592968073 @default.
• W207934189 cites W1719035976 @default.
• W207934189 cites W1808308480 @default.
• W207934189 cites W1854794930 @default.
• W207934189 cites W1966101354 @default.
• W207934189 cites W1967029543 @default.
• W207934189 cites W1967626864 @default.
• W207934189 cites W1971155152 @default.
• W207934189 cites W1972056292 @default.
• W207934189 cites W1973566092 @default.
• W207934189 cites W1975759245 @default.
• W207934189 cites W1978978844 @default.
• W207934189 cites W1984342992 @default.
• W207934189 cites W1984623076 @default.
• W207934189 cites W1987594842 @default.
• W207934189 cites W1991398989 @default.
• W207934189 cites W1996369869 @default.
• W207934189 cites W1997413910 @default.
• W207934189 cites W1999184700 @default.
• W207934189 cites W2003126097 @default.
• W207934189 cites W2011727241 @default.
• W207934189 cites W2013993289 @default.
• W207934189 cites W2014202509 @default.
• W207934189 cites W2017367371 @default.
• W207934189 cites W2022059360 @default.
• W207934189 cites W2022752089 @default.
• W207934189 cites W2023021283 @default.
• W207934189 cites W2023903089 @default.
• W207934189 cites W2025318581 @default.
• W207934189 cites W2027223222 @default.
• W207934189 cites W2034513871 @default.
• W207934189 cites W2035530913 @default.
• W207934189 cites W2037301677 @default.
• W207934189 cites W2041533847 @default.
• W207934189 cites W2041663965 @default.
• W207934189 cites W2045036133 @default.
• W207934189 cites W2047973327 @default.
• W207934189 cites W2061035691 @default.
• W207934189 cites W2068590254 @default.
• W207934189 cites W2073347427 @default.
• W207934189 cites W2075730950 @default.
• W207934189 cites W2076410912 @default.
• W207934189 cites W2076832092 @default.
• W207934189 cites W2082415996 @default.
• W207934189 cites W2082443813 @default.
• W207934189 cites W2085241964 @default.
• W207934189 cites W2085305525 @default.
• W207934189 cites W2088767461 @default.
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• W207934189 cites W2095620419 @default.
• W207934189 cites W2095795974 @default.
• W207934189 cites W2096511986 @default.
• W207934189 cites W2099355205 @default.
• W207934189 cites W2102946764 @default.
• W207934189 cites W2107420413 @default.
• W207934189 cites W2122368087 @default.
• W207934189 cites W2128964866 @default.
• W207934189 cites W2138187317 @default.
• W207934189 cites W2149933413 @default.
• W207934189 cites W2150257621 @default.
• W207934189 cites W2151917872 @default.
• W207934189 cites W2157973470 @default.
• W207934189 cites W2169556962 @default.
• W207934189 cites W2256365303 @default.
• W207934189 cites W2319089859 @default.
• W207934189 cites W2322010248 @default.
• W207934189 cites W2327067203 @default.
• W207934189 cites W2327359646 @default.
• W207934189 cites W2327530675 @default.
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• W207934189 cites W2409358533 @default.
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• W207934189 doi "https://doi.org/10.1007/978-0-585-37970-8_1" @default.
• W207934189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10442164" @default.
• W207934189 hasPublicationYear "1999" @default.
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