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- W2079347509 abstract "Abstract Nonamplified (null) alleles are a common feature of microsatellite genotyping and can bias estimates of allele and genotype frequencies, thereby hindering population genetic analyses. The frequency of microsatellite null alleles in diploid populations can be estimated for populations that are in Hardy–Weinberg equilibrium. However, many microsatellite data sets are from nonequilibrium populations, often with known inbreeding coefficients ( F ) or fixation indices ( F IS or F ST ). Here, we propose a novel null allele estimator that can be used to estimate the null allele frequency and adjust visible allele frequencies in populations for which independent estimates of F , F IS or F ST are available. The algorithm is currently available as an Excel macro that can be downloaded at no cost from http://www.microchecker.hull.ac.uk/ and will be incorporated into the software micro ‐ checker ." @default.
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- W2079347509 date "2005-12-21" @default.
- W2079347509 modified "2023-10-12" @default.
- W2079347509 title "Estimation and adjustment of microsatellite null alleles in nonequilibrium populations" @default.
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- W2079347509 doi "https://doi.org/10.1111/j.1471-8286.2005.01082.x" @default.
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