Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079349601> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2079349601 endingPage "676" @default.
- W2079349601 startingPage "673" @default.
- W2079349601 abstract "Twenty years ago, a genetically determined severe deficiency in alpha1-antitrypsin associated with the early onset of emphysema was reported. 1 Laurell I Eriksson CB. The electrophoretic alpha-1-globulin pattern of serum in alpha-1-antitrypsin deficiency. Scand J Clin Invest. 1963; 15: 132-400 Crossref Google Scholar , 2 Eriksson S. Pulmonary emphysema and alpha-1-antitrypsin deficiency. Acta Med Scand. 1964; 175: 197-205 Crossref PubMed Scopus (323) Google Scholar , 3 Eriksson S. Studies in alpha-1-antitrypsin deficiency. Acta Med Scand. 1965; 177: 41-75 Google Scholar This was the first, and thus far the only, clearly identified heritable factor in the etiology of pulmonary emphysema to be described. However, the prevalence of severe alpha1-antitrypsin deficiency in the general population is too low (less than 0.5 percent) to explain the vast majority of cases of emphysema. It also appears that persons who are heterozygous for the deficiency are no more at risk of developing lung disease than the more than 85 percent of the population without this genetic factor. 4 Bruce RM Cohen BH Diamond EL Fallat RJ Knudson RJ Lebowitz MD et al. Collaborative study to assess risk of lung disease in PiMZ phenotype subjects. Am Rev Respir Dis. 1984; 130: 386-900 PubMed Google Scholar Nevertheless, there is epidemiologic evidence to suggest a familial occurrence of chronic obstructive lung disease. 5 Kueppers F Miller RD Gordon H Hepper NG Offord K. Familial prevalence of chronic obstructive pulmonary disease in a matched pair study. Am J Med. 1977; 63: 336-420 Abstract Full Text PDF PubMed Scopus (124) Google Scholar This is not a new idea. We can trace the concept of emphysema as a hereditary disease to its origins more than a century ago." @default.
- W2079349601 created "2016-06-24" @default.
- W2079349601 creator A5033049703 @default.
- W2079349601 date "1985-05-01" @default.
- W2079349601 modified "2023-10-18" @default.
- W2079349601 title "James Jackson, Jr., The Young Pulmonologist Who Described Familial Emphysema" @default.
- W2079349601 cites W2032703463 @default.
- W2079349601 cites W2034226395 @default.
- W2079349601 cites W2039889139 @default.
- W2079349601 cites W2089695818 @default.
- W2079349601 doi "https://doi.org/10.1378/chest.87.5.673" @default.
- W2079349601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3886316" @default.
- W2079349601 hasPublicationYear "1985" @default.
- W2079349601 type Work @default.
- W2079349601 sameAs 2079349601 @default.
- W2079349601 citedByCount "8" @default.
- W2079349601 countsByYear W20793496012012 @default.
- W2079349601 countsByYear W20793496012015 @default.
- W2079349601 countsByYear W20793496012017 @default.
- W2079349601 crossrefType "journal-article" @default.
- W2079349601 hasAuthorship W2079349601A5033049703 @default.
- W2079349601 hasConcept C126322002 @default.
- W2079349601 hasConcept C137627325 @default.
- W2079349601 hasConcept C142724271 @default.
- W2079349601 hasConcept C177713679 @default.
- W2079349601 hasConcept C2777714996 @default.
- W2079349601 hasConcept C2779134260 @default.
- W2079349601 hasConcept C2780535462 @default.
- W2079349601 hasConcept C2908647359 @default.
- W2079349601 hasConcept C2910768427 @default.
- W2079349601 hasConcept C2983914783 @default.
- W2079349601 hasConcept C2992779976 @default.
- W2079349601 hasConcept C71924100 @default.
- W2079349601 hasConcept C99454951 @default.
- W2079349601 hasConceptScore W2079349601C126322002 @default.
- W2079349601 hasConceptScore W2079349601C137627325 @default.
- W2079349601 hasConceptScore W2079349601C142724271 @default.
- W2079349601 hasConceptScore W2079349601C177713679 @default.
- W2079349601 hasConceptScore W2079349601C2777714996 @default.
- W2079349601 hasConceptScore W2079349601C2779134260 @default.
- W2079349601 hasConceptScore W2079349601C2780535462 @default.
- W2079349601 hasConceptScore W2079349601C2908647359 @default.
- W2079349601 hasConceptScore W2079349601C2910768427 @default.
- W2079349601 hasConceptScore W2079349601C2983914783 @default.
- W2079349601 hasConceptScore W2079349601C2992779976 @default.
- W2079349601 hasConceptScore W2079349601C71924100 @default.
- W2079349601 hasConceptScore W2079349601C99454951 @default.
- W2079349601 hasIssue "5" @default.
- W2079349601 hasLocation W20793496011 @default.
- W2079349601 hasLocation W20793496012 @default.
- W2079349601 hasOpenAccess W2079349601 @default.
- W2079349601 hasPrimaryLocation W20793496011 @default.
- W2079349601 hasRelatedWork W2081701275 @default.
- W2079349601 hasRelatedWork W2390856716 @default.
- W2079349601 hasRelatedWork W2418895538 @default.
- W2079349601 hasRelatedWork W2604605908 @default.
- W2079349601 hasRelatedWork W2895926441 @default.
- W2079349601 hasRelatedWork W2905882916 @default.
- W2079349601 hasRelatedWork W3028892750 @default.
- W2079349601 hasRelatedWork W3031775004 @default.
- W2079349601 hasRelatedWork W3041182916 @default.
- W2079349601 hasRelatedWork W4245507704 @default.
- W2079349601 hasVolume "87" @default.
- W2079349601 isParatext "false" @default.
- W2079349601 isRetracted "false" @default.
- W2079349601 magId "2079349601" @default.
- W2079349601 workType "article" @default.