Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079356413> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2079356413 endingPage "1620" @default.
- W2079356413 startingPage "1617" @default.
- W2079356413 abstract "This chapter reviews the evidence that DNA damage may be involved in chemical-induced cell death. The importance of DNA damage for radiation-induced cell killing has been demonstrated in experiments where the cell nucleus and the cytoplasm are selectively irradiated using suitably constructed beams of ionizing particles. It is shown that when the cytoplasm is the target, the dose required to kill a cell is larger by orders of magnitude than the dose required in the nucleus. A general problem shared by most genotoxic chemicals is that they also damage non-DNA targets, such as RNA, proteins and lipids, and cellular processes in the nucleus or in other organelles including mitochondria, endoplasmic reticulum, plasma membrane, and cytoskeleton. When evaluating the importance of chemical-induced DNA damage in organ toxicity, extranuclear injury has to be taken into consideration." @default.
- W2079356413 created "2016-06-24" @default.
- W2079356413 creator A5006397187 @default.
- W2079356413 creator A5032667185 @default.
- W2079356413 creator A5087288886 @default.
- W2079356413 date "1980-06-01" @default.
- W2079356413 modified "2023-09-28" @default.
- W2079356413 title "Lack of evidence for N-hydroxyacetaminophen as a reactive metabolite of acetaminophen in vitro" @default.
- W2079356413 cites W1971296064 @default.
- W2079356413 cites W2009989821 @default.
- W2079356413 cites W2012730063 @default.
- W2079356413 cites W2043697915 @default.
- W2079356413 cites W2083141208 @default.
- W2079356413 cites W2084992276 @default.
- W2079356413 cites W2093822317 @default.
- W2079356413 cites W2320359099 @default.
- W2079356413 doi "https://doi.org/10.1016/0006-2952(80)90622-x" @default.
- W2079356413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7396994" @default.
- W2079356413 hasPublicationYear "1980" @default.
- W2079356413 type Work @default.
- W2079356413 sameAs 2079356413 @default.
- W2079356413 citedByCount "55" @default.
- W2079356413 countsByYear W20793564132014 @default.
- W2079356413 crossrefType "journal-article" @default.
- W2079356413 hasAuthorship W2079356413A5006397187 @default.
- W2079356413 hasAuthorship W2079356413A5032667185 @default.
- W2079356413 hasAuthorship W2079356413A5087288886 @default.
- W2079356413 hasConcept C143425029 @default.
- W2079356413 hasConcept C1491633281 @default.
- W2079356413 hasConcept C158617107 @default.
- W2079356413 hasConcept C168240541 @default.
- W2079356413 hasConcept C185592680 @default.
- W2079356413 hasConcept C190062978 @default.
- W2079356413 hasConcept C202751555 @default.
- W2079356413 hasConcept C2778106830 @default.
- W2079356413 hasConcept C2780114586 @default.
- W2079356413 hasConcept C2780723820 @default.
- W2079356413 hasConcept C28859421 @default.
- W2079356413 hasConcept C552990157 @default.
- W2079356413 hasConcept C55493867 @default.
- W2079356413 hasConcept C86803240 @default.
- W2079356413 hasConcept C95444343 @default.
- W2079356413 hasConceptScore W2079356413C143425029 @default.
- W2079356413 hasConceptScore W2079356413C1491633281 @default.
- W2079356413 hasConceptScore W2079356413C158617107 @default.
- W2079356413 hasConceptScore W2079356413C168240541 @default.
- W2079356413 hasConceptScore W2079356413C185592680 @default.
- W2079356413 hasConceptScore W2079356413C190062978 @default.
- W2079356413 hasConceptScore W2079356413C202751555 @default.
- W2079356413 hasConceptScore W2079356413C2778106830 @default.
- W2079356413 hasConceptScore W2079356413C2780114586 @default.
- W2079356413 hasConceptScore W2079356413C2780723820 @default.
- W2079356413 hasConceptScore W2079356413C28859421 @default.
- W2079356413 hasConceptScore W2079356413C552990157 @default.
- W2079356413 hasConceptScore W2079356413C55493867 @default.
- W2079356413 hasConceptScore W2079356413C86803240 @default.
- W2079356413 hasConceptScore W2079356413C95444343 @default.
- W2079356413 hasIssue "11" @default.
- W2079356413 hasLocation W20793564131 @default.
- W2079356413 hasLocation W20793564132 @default.
- W2079356413 hasOpenAccess W2079356413 @default.
- W2079356413 hasPrimaryLocation W20793564131 @default.
- W2079356413 hasRelatedWork W1605357185 @default.
- W2079356413 hasRelatedWork W2029114201 @default.
- W2079356413 hasRelatedWork W2094289296 @default.
- W2079356413 hasRelatedWork W2159265487 @default.
- W2079356413 hasRelatedWork W2415944105 @default.
- W2079356413 hasRelatedWork W3090876536 @default.
- W2079356413 hasRelatedWork W3105163292 @default.
- W2079356413 hasRelatedWork W35137212 @default.
- W2079356413 hasRelatedWork W4213306749 @default.
- W2079356413 hasRelatedWork W4246742528 @default.
- W2079356413 hasVolume "29" @default.
- W2079356413 isParatext "false" @default.
- W2079356413 isRetracted "false" @default.
- W2079356413 magId "2079356413" @default.
- W2079356413 workType "article" @default.