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- W2079371963 abstract "Summary The cerebrospinal fluid of 55 patients with acute paralytic poliomyelitis and of 19 healthy children (9 additional ones at a later date) as controls was examined for glutamic oxalacetic transaminase (GOT) activity. On the basis of severity of paralysis, the cases were clinically classified as mild, moderate, severe, and extensive. The data suggest that: 1. The cerebrospinal fluid of healthy infants and young children has no measurable GOT activity. 2. In most cases of acute paralytic poliomyelitis there is a rise in transaminase activity in the cerebrospinal fluids, especially during the first one or two weeks following the onset of paralysis, suggesting the possibility of injury to the nervous tissue. 3. The increased transaminase activity of the early phase of the disease gradually declines to normal. 4. The height of transaminase activity showed no correlation with the severity of the disease. 5. No correlation has been found between the serum transaminase and that of the cerebrospinal fluid in cases of paralytic poliomyelitis." @default.
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- W2079371963 date "1961-07-01" @default.
- W2079371963 modified "2023-09-27" @default.
- W2079371963 title "Evaluation of transaminase activity in the cerebrospinal fluid in paralytic poliomyelitis" @default.
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- W2079371963 doi "https://doi.org/10.1016/s0022-3476(61)80210-2" @default.
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