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• W2079387637 abstract "Cigarette smoking is commonly associated with weight loss and mechanisms for these weight changes are still elusive. Ghrelin is a peptide hormone that works in a neuroendocrine fashion to stimulate hunger and the desire for food intake. Ghrelin is also secreted in saliva, probably to enhance food taste. In the current study, we tested the direct impact of acute cigarette smoking on total ghrelin found in saliva. Methods . Blood and saliva samples were collected from 30 healthy nonsmoker male volunteers before and after one-cigarette smoke. Total ghrelin in serum and saliva was measured by ELISA based method. Results . Data showed a statistically significant reduction in salivary ghrelin after smoking<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mo stretchy=false>(</mml:mo><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.0001</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>. In serum, total ghrelin levels were not affected before and after smoking<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mo stretchy=false>(</mml:mo><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.1362</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>. Additionally, positive correlation was observed between serum and salivary ghrelin before smoking<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mi>(r</mml:mi><mml:mo>=</mml:mo><mml:mn>0.4143</mml:mn></mml:math>and<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.0158)</mml:mn></mml:math>; however, this correlation was lost after smoking<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mo stretchy=false>(</mml:mo><mml:mi>r</mml:mi><mml:mo>=</mml:mo><mml:mn>0.1147</mml:mn></mml:math>and<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.5461</mml:mn><mml:mo stretchy=false>)</mml:mo></mml:math>. Conclusion . Acute one-cigarette smoking can negatively affect ghrelin levels in saliva that might contribute to the dull food taste in smokers." @default.
• W2079387637 created "2016-06-24" @default.
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• W2079387637 date "2014-01-01" @default.
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• W2079387637 title "Acute One-Cigarette Smoking Decreases Ghrelin Hormone in Saliva: A Pilot Study" @default.
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• W2079387637 doi "https://doi.org/10.1155/2014/575671" @default.
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