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• W2079394085 abstract "A procedure for the radiosynthesis of aliphatic [18F]trifluoromethyl groups by reacting 1,1-difluorovinyl precursors with [18F]fluoride ions, resulting in the equivalent of direct nucleophilic addition of H[18F]F, has been developed. A variety of 18F-labelled model compounds were then obtained and two potential [18F]radiotracers were synthesised by a two step process starting from 1,1-difluorovin-2-yl 4-toluenesulfonate. The method is widely applicable for the synthesis of novel radiotracers in high radiochemical yields and good specific activity." @default.
• W2079394085 created "2016-06-24" @default.
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• W2079394085 date "2011-01-01" @default.
• W2079394085 modified "2023-10-16" @default.
• W2079394085 title "A simple, rapid procedure for nucleophilic radiosynthesis of aliphatic [18F]trifluoromethyl groups" @default.
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• W2079394085 doi "https://doi.org/10.1039/c1cc15342k" @default.
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