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• W2079396957 abstract "Irradiation with UV-B, a component of natural sunlight, initiates systemic immunosuppression of delayed-type hypersensitivity responses. This may be a fundamental regulatory mechanism, controlling the interaction between mammals and potentially deleterious environmental UV radiation. Here, Frances Noonan and Edward De Fabo assess the evidence that suppression is initiated by the photoisomerization of trans-urocanic acid (UCA) in the stratum corneum, discuss the significance of this mechanism for skin cancer outgrowth and propose applications for UCA in transplantation." @default.
• W2079396957 created "2016-06-24" @default.
• W2079396957 creator A5065354917 @default.
• W2079396957 creator A5070664762 @default.
• W2079396957 date "1992-01-01" @default.
• W2079396957 modified "2023-10-16" @default.
• W2079396957 title "Immunosuppression by ultraviolet B radiation: initiation by urocanic acid" @default.
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• W2079396957 doi "https://doi.org/10.1016/0167-5699(92)90005-r" @default.
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• W2079396957 hasPublicationYear "1992" @default.
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