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- W2079398445 endingPage "7" @default.
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- W2079398445 abstract "Primary intracerebral hemorrhage (ICH) is associated with a high mortality rate and severe morbidity. The treatment of choice is still controversial, given that data from several clinical trials have not provided convincing evidence to support the efficacy of surgical clot removal. Favoring early clot removal is evidence that the limited release of specific neurotoxins associated with the breakdown products of hemoglobin underlies secondary brain injury. Attention has therefore shifted to perilesional brain injury, especially brain edema, as a potential target for therapeutic intervention in patients with ICH. In this review the authors address current understanding of the causes of edema formation following ICH and the treatment options, which are mostly supportive in nature." @default.
- W2079398445 created "2016-06-24" @default.
- W2079398445 creator A5022056595 @default.
- W2079398445 creator A5053643750 @default.
- W2079398445 date "2007-05-01" @default.
- W2079398445 modified "2023-10-06" @default.
- W2079398445 title "Brain edema after intracerebral hemorrhage: mechanisms, treatment options, management strategies, and operative indications" @default.
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- W2079398445 doi "https://doi.org/10.3171/foc.2007.22.5.7" @default.
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