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• W2079400424 abstract "In everyday life, the brain is bombarded with a multitude of concurrent and competing stimuli. Only some of these enter consciousness and memory. Attention selects relevant signals for in-depth processing depending on current goals, but also on the intrinsic properties of stimuli. We combined behavior, computational modeling, and functional imaging to investigate mechanisms supporting access to memory based on intrinsic sensory properties. During fMRI scanning, human subjects were presented with pictures of naturalistic scenes that entailed high levels of competition between possible target objects. Following a retention interval of 8 s, participants judged the location (same/different) of a target object extracted from the initial scene. We found that memory performance at retrieval increased with increasing object salience at encoding, indicating a “prior entry” for salient information. fMRI analyses revealed encoding-related activation in the posterior parietal cortex, selectively for salient objects that were later remembered. Moreover, parietal cortex showed increased functional coupling with the medial-temporal lobe, for remembered objects only. These findings reveal a parietotemporal circuit that integrates available sensory cues (based on attention-grabbing saliency signals) and current memory requirements (storing objects' locations) to encode object-related spatial information in working memory." @default.
• W2079400424 created "2016-06-24" @default.
• W2079400424 creator A5040704077 @default.
• W2079400424 creator A5079975504 @default.
• W2079400424 date "2013-02-27" @default.
• W2079400424 modified "2023-09-25" @default.
• W2079400424 title "Visual Salience Improves Spatial Working Memory via Enhanced Parieto-Temporal Functional Connectivity" @default.
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• W2079400424 doi "https://doi.org/10.1523/jneurosci.4138-12.2013" @default.
• W2079400424 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3695392" @default.
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